Paper Information

Title: 

STAPHYLOCOCCUS AUREUS INDUCE SEVERITY IN ATOPIC DERMATITIS (REPORT OF A CASE)

Type: PAPER
Author(s): KAMALI S.*,POURPAK Z.
 
 *IMMUNOLOGY, ASTHMA AND ALLERGY RESEARCH INSTITUTE, CHILDREN MEDICAL CENTER, MEDICAL SCIENCES/UNIVERSITY OF TEHRAN, TEHRAN, IRAN
 
Name of Seminar: BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY
Type of Seminar:  CONGRESS
Sponsor:  IRAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES
Date:  2007Volume 6
 
 
Abstract: 

INTRODUCTION: Atopic dermatitis (AD) is a kind of dermatosis typically found among children. The major symptom is itching, which may vary in intensity. The disease presents a chronic course; intensity, and discomfort of symptoms cause serious implications in the life of patients and their families.
The incidence of such atopy has been increasing over the last decades, especially in industrialized countries, maybe due to external factors, which foster lesions severity and consequently bring some difficulties to adaptation to school, social and family life.
CASE REPORT: A seven-month-old girl was referred to Department of Immunology, Asthma and Allergy of Children Medical Center, Tehran University of Medical Sciences. She had severe atopic dermatitis. Her skin lesions were infected with Herpes (Eczema herpeticum). Her SCORAD was 72.2 at the time of arrival and her Staphyloccocus Aureus culture was positive. She was treated with Acyclovir, cephalexin and hydroxyzine. After 2 weeks without any change in treatment and environmental factors she feels better, her Staphyloccocus Aureus culture became negative, her symptoms and signs had decreased dramatically; her SCORAD was 50.7 then.
DISCUSSION: Atopic dermatitis (AD) patients are prone to secondary infections with organisms such as Herpes simplex virus and staphylococcus aureus; therefore any change in appearance of skin lesions should arouse the suspicion of the probable infection. Early treatment with antibiotics can prevent severe complication. It is recommended that all Atopic Dermatitis patients be considered for Staphyloccocus Aureus culture, Staphyloccocus Aureus Antibody evaluation and prophylactic antistaphyloccocal treatment especially in severe cases.

 
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