Paper Information

Title: 

CARDIAC VAGAL ACTIVITY IS DECREASED IN PATIENTS WITH CORONARY ARTERY DISEASE: A COMPARISON BETWEEN RESPIRATORY SINUS ARRHYTHMIA AND ETT TEST RESULTS

Type: POSTER
Author(s): GHASEMI RASOUL,FOROUTAN ABAS,ERFANIAN OMIDVAR A.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

Heart rate variability that is the amount of heart rate Fluctuations around the mean heart rate can be used as tool to assess cardiovascular autonomic system. The variation of heart rate induced by respiration is called Respiratory sinus arrhythmia (RSA). RSA reflects function of autonomic heart rate control system, especially cardiac parasympathetic activity. Major life threatening arrhythmias and acute coronary events, have been suggested to be triggered by the activation of the autonomic nervous system in patients with coronary artery disease. Therefore in this study we intend to evaluate spectral components of HRV in deep respiration test in patients with atypical chest pain before diagnostic exercise test and compared these components in patients with positive or negative exercise test result with a control group.
Method: 12 CAD patients with positive exercise test, 46 people with negative and 10 people with normal coronary artery as control group participated in this study. Before exercise test following autonomic test was performed. 2 minute rest followed by 1 minute of deep breathing at 6 breath/minute. While recording was performed. Recordings were analyzed with time-frequency method. (Bessel). Then the mean of power of HF and respiratory induced increment in HF were compared in each test separately. By one way ANOVA.
Results: Our study shows the power of HF (an indicator of parasympathetic activity) was lower in CAD patients with positive exercise test during deep respiration, in addition respiratory induced increment in HF power was lower in those patients.
Conclusion: Our study suggests that cardiac Vagal activity is depressed and sympathovagal balance shifted toward sympathetic predominance in patients with coronary artery disease and our study showed that deep breathing test is the most sensitive test to show this reduction in cardiac vagal activity.

 
Keyword(s): HEART RATE VARIABILITY, RESPIRATORY SINUS ARRHYTHMIA, CORONARY ARTERY DISEASE, CARDIAC VAGAL ACTIVITY
 
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