Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Title: 

THE EFFECT OF ALPRAZOLAME ON INSULIN BLOOD LEVEL IN RAT

Type: SPEECH
Author(s): VAHIDI ALI REZA*,AFKHAMI M.,VAHIDI M.Y.
 
 *DIABETES RESEARCH CENTER, SHAHEED SADOUGHI UNIVERCITY OF MEDICAL SCIENCES, YAZD, IRAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

Chronic diabetes mellitus is one of the famous metabolic diseases in the world and one of the main complications in developing countries. Many people in the world suffer from this disease and they should use oral anti diabetic drugs. They are sometime resistant to these agents and some of them should use injecting insulin that its compliance is difficult. Therefore, it is very important to find out some agents as alternatives to those mentioned. In the present study the effect of alprazolame on the blood level of insulin was examined. The experiment was carried out on 20 male adult rats weighting 180-200g. Animals were chosen randomly and divided into four groups including control and three cases groups that received alprazolame at different doses of 0.5, 1 and 2 mg/kg by intrapretonial injection method. Blood insulin levels were measured at 0, 2, 4 and 6 hours after injection. Our findings showed that blood insulin level increased in response to alprazolame injection in a dose dependent manner. Maximum increment was observed at the dose of 2mg/kg p<0.05. Inconclusion, we know that cortisol can increase the blood sugar by stress and anxiety. Alprazolame by decreasing the stress and anxiety may diminish cortisol secretion and it can lead to the reduction of blood sugar.

 
Keyword(s): INSULIN, ALPRAZOLAME, BLOOD SUGAR, CORTISOL
 
 
Yearly Visit 41   tarjomyar
 
Latest on Blog
Enter SID Blog