Paper Information

Title: 

CLINICAL STUDY ON THE EFFICACY OF ORALLY ADMINISTERED CRUSHED FRESH GARLIC IN CONTROLLING PSEUDOMONAS AERUGINOSA INFECTION IN BURN PATIENTS WITH VARYING BURN SIZES

Type: POSTER
Author(s): PIPELZADEH M.H.*,GHALAMBOR A.A.A.
 
 *DEPARTMENT OF PHARMACOLOGY, SCHOOL OF MEDICINE, AHWAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES, AHWAZ, IRAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

The aim of the present study was to evaluate the effectiveness of orally administered crushed fresh garlic cloves in the control of P aeruginosa burn wound infection among patients with different burn sizes. In this study, three groups of patients with varying burns sizes (>70, <70 but >45 and <45 but >20% of TBSA) were serially and randomly allocated into two equal number of control and treatment subgroups and matched for age, sex, area and cause of burn. Treatment group received two crushed garlic coves mixed with yogurt with their daily lunch meal, while controlgroup received yogurt only. The time P aeruginosa burn wound infection was considered as end point for study among the selected groups. The results showed that the number of patients who developed P aeruginosa burn wound infection was significantly reduced among the garlic-treated subgroup in the group with <45 but >20% of TBSA burn in the first week of hospitalization. No significant differences in other groups of patients were recorded. In conclusion it seems that fresh crushed garlic cloves canbe used as a supplementary herbal medicinal agent in delaying of Paeruginosa burn wound infection in patients with moderate burn injuries. Prudently, this hypothesis needs to be tested at a higher dosage levels on a larger number of patients.

 
Keyword(s): P AERUGINOSA, BURN WOUND SIZE, FRESH GARLIC CLOVE, BURN WOUND INFECTION
 
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