Paper Information

Title: 

ASSESSMENT OF ANALGESIC EFFECTS OF CM LOTION IN MOUSE

Type: POSTER
Author(s): MAHMOUDIFAR FARHAD,MAHMOUDIFAR FARNAZ,VAEZ A.,AJOUDANI M.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

The active substance of CM lotion inhibits prostaglandins and other inflammatory mediators. Therefore it can remove the inflammation and pain. The active substance of this lotion contains 50% of celery essence (Apium Graveolens) from the family of Umbeliferae and 50% of mint essence (Mentha Spicata) from the family of Labiatae.
In this study 24 mice were selected and divided into two groups of experimental group (case group, n=12) and control group (n=12). We used Tail-flick (T.F.L.) method for determining the analgesic effects of the lotion. With the intensity of 40, we applied 1 ml of CM lotion on the tail of every mice of the experimental group. 30 minutes later the mice put in T.F.L machine and the apparatus registered the pain endurance time for each mouse. The average time was 5.35 seconds for experimental group and 3.2 seconds for the control group.
This study showed that the CM lotion may increase the pain endurance mean time (p<0.05).

 
Keyword(s): CM LOTION , T.F.L MACHINE
 
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