Paper Information

Title: 

DIFFUSION PATTERN OF ACIDIC SUGAR COMPOUNDS IN PROCESS OF PLACENTAL DEVELOPMENT IN RAT

Type: POSTER
Author(s): MAHMOUDI MALIHEH*,KHAYATZADEH J.,JALALI MAHDI,TEHRANIPOUR M.
 
 *MASHHAD AZAD UNIVERSITY
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

The placenta is a vascular organ within the uterus, connected to the fetus by the umbilical cord; it is the structure through which the fetus is nourished. In the rat placenta, three regions can be identified: the decidua basalis, the basal zone, and the labyrinth. In many articles, diffusion of different sugar compounds has been related with the process of placental development, its function, and physiology. In present study, the presence of acidic and sulfated sugar compounds was studied in response to staining with alcian blue (pH1) and carboxylated acidic sugar compounds in response to alcian blue (pH2.5) at of 16, 18, and 20 days of pregnancy in rat placenta. Data were represented in form of observed color intensity tables in every stage. Results showed that in pH1 in all days, maternal part of placenta (deciduas basalis) had a weak response to alcian blue, whereas in embryonic part of the placenta (labyrinth zone), this response was weaker. In pH2.5, color intensity was also observed with the same diffusion pattern in pH1. However, comparison of color intensity response for two types of alcian blue applied showed that color intensity was weaker in pH2.5. Staining in final days did not show a significant change compared to previous days. In regard to diffusion pattern of time–place of mentioned compounds, it seems that in all stages of placental development, decidua basalis layer has more concentration of acidic sugar compounds (carboxylic and sulfated) incomparison with other parts. Also, no remarkable change was observed in concentration of these compounds in different days. These observations are probably related with placental function in maternal-embryonic exchanges of gases and metabolites.

 
Keyword(s): ACIDIC SUGAR COMPOUNDS, PLACENTA, RAT
 
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