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Paper Information

Title: 

EFFECT OF ALCOHOLIC EXTRACT OF DOREMA AUCHREI ON HOMOGRAM IN ADULT MALE RAT

Type: POSTER
Author(s): MOKHTARI MOKHTAR*,SHARIFI ESFANDIAR,PARANG A.
 
 *DEPARTMENT OF BIOLOGY, KAZEROUN BRANCH, ISLAMIC AZAD UNIVERSITY
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

Dorema aucheri is from umbrella family plants and the residents of south country use this plant as food and they believe that is has drug drugperties. In this research the effect of different amounts of Dorema aucheri extract on homogram in adult male rats were studied. 40 adult male rats divided into the following groups: control, sham operated and experimental groups. Experimental groups subdivided into three and the plant alcoholic extract with 100, 200, 400 (mg/kg) received for 30 days. The sham group recieved ventricle of the heart was done and in the all of the groups by using lab usual methods, the whole numbers of white Blood Cell (WBC), Red Blood Cell (RBC), hematocrit , MCV, MCH, MCHC, lymphocyte percentage and monocytes and platelets were measured and the received results analysed.
The results showed that using Dorema aucheri alcoholic extract at the end of 30th day caused increasing in monocytes numbers. A great difference in experiment and control group was observed. Also the rate of plate at the end of 30th day showed a great decrease to the control group.
Considering the results of this research, presumably plant extraction, for having flawnoiedic compounds that also have anti oxidant properties, it causes monocytes increasing. Also by haltering ca2+ enterance, IP3Proelucing and phosphoylation of some proteins from human platelets stimulated with PAF (platelets activating factor) flawnoieds cause platelets number decreasing and also they react with arachidonic Acid.
There fare they cause preventing from producing Thromboxane A2 platelets and cancludingly cause platelets decreasing.

 
Keyword(s): DOREMA AUCHERI, HOMOGRAM, RAT
 
 
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