Paper Information

Title: 

APPLICATION OF GINA GUIDELINES ON TREATMENT EEFICACY IN ASTHMATIC PATIENTS

Type: PAPER
Author(s): BOSKABADI M.H.*,RAHIMI N.,DEHNAVI D.,REZAEI TALAB F.
 
 *DEPT. OF PHYSIOLOGY, GHAEM MEDICAL CENTRE, MASHHAD UNIVERSITY OF MEDICAL SCIENCES, MASHHAD, I.R., IRAN
 
Name of Seminar: BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY
Type of Seminar:  CONGRESS
Sponsor:  IRAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES
Date:  2007Volume 6
 
 
Abstract: 

Asthma management is a major concern and many guidelines were developed regarding the management procedure of this debases special Global Initiative Strategy for treatment of asthma (GINA). However, these gridlines is poorly applied in under deployment countries. Therefore in the present study, an attempt has been made to examine the effect of application of GINA guideline on treatment efficacy in asthmatic patients in our country. Thirty-one asthmatic adults were randomly divided into control group (15 patients, male and female) and study group (15 patients, male and female) and were studied for 2 months. Asthma symptom score (SS), asthma severity, frequency of symptoms/week and wheezing were recorded at the beginning (first visit), one month after treatment (second visit) and at the end of the study (third visit). Pulmonary function tests (PFTs) including forced vital capacity (FVC), forced expiratory volume in one second (FEV1), maximal mid expiratory flow rate (MMEF), peak expiratory flow (PEF), maximal expiratory flow at 75%, 50%, and 25% of the FVC (MEF75, MEF50, and MEF25 respectively) were also measured and the drug regiment of the patients was evaluated at three different visit. All asthma symptoms, frequency of asthma symptoms/week, chest wheezing and pulmonary function test (PFT) values in study group, were significantly lower in second and third visits than first visit (p<0.05 t0 p<0.001). In second and third visits all symptoms in the study group improved and were significantly different from control group (p<0.05 to p<0.001). The usages of drugs in the study group were decreased at the end of the study. The results obtained in the study showed that treatment of asthmatic patients according to GINA guideline can lead to significant improvement in symptoms, severity of the diseases, wheeze, and PFT values.

 
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