Paper Information

Title: 

EVALUATION OF IFN-γ SERUM LEVEL IN NEPHROPATHIC TYPE 2 DIABETIC PATIENTS

Type: POSTER
Author(s): SHOKRIZADEH M.*,TALEBI MOHAMMAD,KAZEMI MOHAMMAD,SHAMSIZADEH ALI,REZVANI M.E.
 
 *DEPARTMENT OF PHYSIOLOGY, SCHOOL OF MEDICINE, RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES, RAFSANJAN, IRAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

Immune system related factors including cytokines are recently under research for their crucial roles in diabetes and subsequent complications of this disease. The present study was aimed to examine the serum level of IFN- g in type 2 diabetic patients with nephropathic complications. Serum samples were obtained from 100 type 2 diabetic patients suffering from nephropathy and 100 healthy controls. Serum level of IFN- g was analysed by ELISA. Results of this study showed that the mean serum level of IFN- g in nephropathic patients (16.09±2.04 pg/ml) was significantly higher than healthy controls (4.03±1.00pg/ml) (P<0.001). Due to the elevated level of IFN-g in nephropathic patients, it can be concluded that immune system may be involved in nephropathic complication of type 2 diabetes.

 
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