Paper Information

Title: 

THE EFFECT OF SWIMMING STRESS ON PLASMA LEPTIN AND CORTICOSTERONE LEVEL IN FEMALE AND MALE RATS

Type: POSTER
Author(s): ZAREEIAN P.*
 
 *DEPARTMENT OF PHYSIOLOGY, ARTESH UNIVERSITY OF MEDICAL SCIENCES
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

The aim of this study was to investigate the effect of acute swimming stress on plasma corticosterone and leptin levels in female and male rats.
Forthy adult male (n=20) and female (n=20) Sprague-Dawley rats (200-250 g weight) were used. The leptin and corticosterone levels were measured following swimming stress (10 minutes: 25oC). Plasma leptin and corticosterone were measured by ELISA system. The plasma leptin levels were significantly increased in female (2.34±0.09 vs 4.49±0.2 ng/ml: p=0.000) and male (2.49±0.1 vs 4.36 ±0.2ng/ml:p=0.000) rats by swimming stress. In addition, Corticosterone levels were significantly increased in female (90.9±18.3 ng/ml vs 153.4 ±5.4 ng/ml: p<0.01) and male (81.1 ±24.7ng/ml vs 130.6 ±9.6 ng/ml: p<0.05) rats by swimming stress. There was no significant differences in leptin level between non- stressed and stressed female and male rats.
Conclusions: The present results show that leptin secretion is not sex dependent.

 
Keyword(s): LEPTIN, CORTICOSTERONE, SWIMMING STRESS
 
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