Paper Information

Title: 

THE E FFECT OF URTICA DIOICA BOILING ON SERUM GLUCOSE, INSULIN AND LIPIDS PROFILE IN DIABETIC MALE RATS WHICH INDUCED BY STREPTOZOTOCINE (STZ)

Type: POSTER
Author(s): SHAHRAKI M.R.*,MIRSHEKARI H.,SHAHRAKI A.R.
 
 *DEPARTMENT OF PHYSIOLOGY, FACULTY OF MEDICINE, ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES, ZAHEDAN, IRAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

Urtica dioica is a traditional treatment for antihypertensive and antilipidemic and antidiabetic. The aim of this survey was to evaluate the effect of Urtica dioica boiling on serum glucose insulin and lipids in diabetic male rats which induced by stereptozotocin.
The experiment was performed on 22 Wistar-Albino male rats, that were diabetic by 65 mg/kg,ip STZ and divided in control and test group randomly. Test group received 60-40 ml boiling of Urtica dioica for 4 week, but the control group received the same volume of tap water. At the end animals were anesthetized, sacrificed and blood samples were collected. Serum glucose insulin and lipids were measured. Obtained data were analyzed by SPSS v.11, via Student T-test. Results were expressed as mean±SD and P<0.05 were recognized significant.
Results showed that serum glucose, cholestrol and triglyserid were significantly decreased in male rats which received Urtica dioica boiling, compared with those of control group, but serum insulin and weight of this group were significantly increased with those of control group.
These results indicated that Urtica dioica boiling cause decreased blood FBS and improved serum lipides in diabetic male rats which induced by STZ. Furthes studies were showed the exact mechanism.

 
Keyword(s): URTICA DIOICA, LIPOPRPTEIN, RAT, GLUCOSE
 
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