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Paper Information

Title: 

RECURRENT ANAPHYLAXIS: A PROBLEM IN FOOD ALLERGIC CHILDREN

Type: PAPER
Author(s): AKRAMIAN R.*,POURPAK Z.,GHOJEZADEH L.,SHOKOUHI R.,MANSOURI M.,BEMANIAN H.,MOEIN M.
 
 *IMMUNOLOGY, ASTHMA AND ALLERGY RESEARCH INSTITUTE, CHILDREN MEDICAL CENTER, MEDICAL SCIENCES/UNIVERSITY OF TEHRAN, TEHRAN, IRAN
 
Name of Seminar: BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY
Type of Seminar:  CONGRESS
Sponsor:  IRAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES
Date:  2007Volume 6
 
 
Abstract: 

Background: Anaphylaxis is a generalized and potentially life-threatening clinical syndrome. We studied recurrences of anaphylaxis carried out in children who referred to Immunology, Asthma and allergy center. (IAARI)
Materials & Methods: Children referred to the clinic of allergy with a previous diagnosis of anaphylaxis were considered in this study (2003-2006). A detailed clinical history and the number of attacks were recorded. For all of the patients, skin prick tests and specific IgE measurement were performed for suspected allergens.
Results: 39 anaphylactic patients (1m to 13 yrs) were entered in this study. 48/1% of patients were male and 24/1% were female. Causative allergens were determined due to clinical history and laboratory tests. 6 (15%) patients had only one episode of anaphylaxis, 10(25%) patients had two episodes while others (58%) had more episodes of anaphylaxis in their life.
Maximum attack number of anaphylaxis was 7 which were due to milk in 4 patients and wheat in 1 patient, also 3 cases of multifactorial food anaphylaxis were identified for the first time. All of them were sensitive to milk, wheat and egg and case 1 and 2 were also sensitive to soya beans.
Conclusion: These data remind the physicians of high recurrences of food anaphylaxis and multifactorial food anaphylaxis. Performing prick test and measurement of specific IgE for common food allergens is suggested after stabilizing patients in the first episode of anaphylaxis. Anaphylactic patients should always have epinephrine autoinjector device with themselves.

 
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