Paper Information

Title: 

EFFECT OF CHRONIC SWIMMING STRESS ON SERUM BUN, CREATININE, NA+ AND K+ CONCENTRATIONS IN ADULT MALE RATS

Type: POSTER
Author(s): KARGAR JAHROMI H.*,ZAREEIAN P.,SOTOUDEH A.R.,JOUHARI H.A.
 
 *DEPT. OF BIOLOGY, ISLAMIC AZAD UNIVERSITY JAHROM BRANCH, YOUNG RESEARCHERS CLUB
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2009Volume 19
 
 
Abstract: 

BUN and creatinine explants rate of functional kidney. Na+ is the most of ions in the extra cellular fluid and K+ is more important cations in the intra cellular fluid. The aim of the present study investigation effects chronic swimming stress and HPA axis on some of serum biochemical factors. In this investigation, we divided 40 male rats to 4 groups: normal, normal with stress, sham (surgery) and adrenalectomy. The animals in stress group were swim in 25C water for continuous 7 days, 10 minutes each day.
Stress, sham and adrenalectomy decreased BUN and creatinine levels (p<0.001). Stress and surgery increased Na level but adrenalectomy does not significant effect (p<0.001, p<0.001, p=0.73). Stress and surgery decreased K level but adrenalectomy increased it.
Conclusion: Stress and surgery decreased BUN and creatinine levels, probably via reduce feeding and body muscle mass. Adrenalectomy deleted effects of glucocorticoids on proteins catabolism, also decreased creatin phosphate level, these cause to decrease BUN and creatinine levels. Stress and surgery increased the functions of sympathetic system and aldosterone secretion; these cases increased Na level and decreased K+ level.
Lack of adrenalectomy effect on Na+ level through the usage of physiology serum. Adrenalectomy decreased aldosterone concentrations that result a rise in K level.

 
Keyword(s): SWIMMING STRESS, BUN, CREATININE, NA+, K+
 
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