Paper Information

Title: 

ASSESSMENT OF IGE ANTIBODIES LEVELS IN SERUM AMONG DRIVERS WITH ASTHMA IN TEHRAN: CASE-CONTROL STUDY

Type: PAPER
Author(s): AGIN KH.*
 
 *LOQMAN HAKIM TEACHING HOSPITAL, PULMONARY WARD, SHAHEED BEHESHTI UNIVERSITY OF MEDICAL SCIENCES
 
Name of Seminar: BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY
Type of Seminar:  CONGRESS
Sponsor:  IRAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES
Date:  2007Volume 6
 
 
Abstract: 

Introduction: Asthma is an inflammatory disease which triggered by a variety factors such as air pollutants. High concentrations of Formaldehyde and polycyclic aromatic hydrocarbons (PAHs) are found in traffic density of ambient air in large cities and may cause respiratory allergic responses in human beings and can be a potential factor in developing occupational asthma as well as exacerbated ever asthma. The PAHs from motor engine are as pro-inflammatory compounds and enhanced IgE responses. The aim of the study was to compare IgE levels in serum between drivers and non-drivers with asthma.
Materials and methods: Eighty-five drivers with asthma, as case group, and one hundred-fifthly non-drivers with asthma, as control groups, were sequentially enrolled among outpatient clinic of respiratory disorders. Age, sex matched was performed between groups of study. Asthma diagnosed based on the ATS criteria. IgE antibodies in serum measured according to manufacture recommendation.
Results: The mean age in drivers was recorded 47.56±10.41 SD. The mean white blood cells were seen 7809.41±2375.35 SD. The eosinophil proportion was 2.92±2.03 SD. The mean IgE antibodies were 232.60±250.83 SD.
The mean age in control groups was 47.90±10.29 SD. The WBC was observed 7648.67±2486.73 SD. The eosinophil proportion was recorded 3.32±2.54 SD. The IgE levels were found 236.34±253.23 SD.
The independent samples T test was carried out between IgE variables. P value was greater than 0.05.
Discussion: No significant difference was noted between IgE levels in both groups. The result may be under the influence of highly significance of air pollutants in Tehran.

 
Keyword(s): ASTHMA, DRIVERS, IGE ANTIBODIES, AIR POLLUTANTS
 
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