Paper Information

Title: 

EVALUATION OF BREATH ALCOHOL ANALYSIS IN DETECTION OF ALCOHOL ABUSE IN REFERED INDIVIDUALS TO FORENSIC TOXICOLOGY LABORATORY, LEGAL MEDICINE ORGANIZATION (LMO) OF ISLAMIC REPUBLIC OF IRAN

Type: SPEECH
Author(s): SOLTANINEZHAD K.,FARYADI M.,AKHGARI M.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF TOXICOLOGY
Type of Seminar:  CONGRESS
Sponsor:  SOCIETY OF TOXICOLOGY
Date:  2004Volume 8
 
 
Abstract: 

ALCOHOL ABUSE IS ONE OF THE MOST IMPORTANT PROBLEMS IN CULTURAL, SOCIAL AND MEDICAL ASPECT. IN FORENSIC MEDICINE, IT IS WELL KNOWN THAT ALCOHOL CAN CAUSE ADVERSE EFFECTS ON CENTRAL NERVOUS SYSTEM AND INDUCED CRIMINAL AND ANTI-SOCIAL BEHAVIORS AND INCREASE ACCIDENTS AND VIOLENT DEATHS. THEREFORE THE ALCOHOL ANALYSIS IN BIOLOGICAL SAMPLES IS THE MOST FREQUENT ANALYSIS, WHICH PERFORMED IN FORENSIC TOXICOLOGY LABORATORIES AND HAS AN IMPORTANT ROLE IN SPECIFYING OF CRIMES IN FORENSIC MEDICINE. BLOOD AND URINE ALCOHOL DETERMINATIONS WERE PERFORMED BY MANY TYPES OF ANALYTICAL METHODS SUCH AS CHEMICAL TESTS, PLASMA OSMOLARITY, ENZYMATIC AND GAS CHROMATOGRAPHY (GC) METHODS. THE DISADVANTAGES OF THESE METHODS ARE EXPENSIVENESS, TIME-CONSUMING AND INVASIVE SAMPLING. FROM THIS VIEW, A RAPID, SIMPLE AND RELIABLE TEST TO QUALITATIVE AND QUANTITATIVE DETECTION OF ALCOHOL IN BLOOD IS NECESSARY TO FORENSIC LABORATORY. BREATH ALCOHOL ANALYSIS HAS BECOME A WIDELY USED METHOD IN QUALITATIVE AND QUANTITATIVE DETERMINATION IN SUSPECTED CASES. THIS STUDY WAS DESIGNED TO EVALUATE THE BREATH ALCOHOL ANALYSIS IN ALCOHOL ABUSERS, WHICH REFERRED TO FORENSIC TOXICOLOGY LABORATORY OF LEGAL MEDICINE ORGANIZATION (LMO).METHODS: THIS STUDY WAS PERFORMED ON 200 MAN REFERRED TO FORENSIC TOXICOLOGY LABORATORY OF LMO. FOR BREATH ALCOHOL ANALYZING, WE USED BREATH ALCOHOL ANALYZER (LIFELOC, FC-20, USA). AFTER CALIBRATION OF DEVICE BY DRY GAS CALIBRATOR, EACH CASE BLOWS HIS END-EXHALE AIR INTO DEVICE THROUGH MOUTHPIECE FOR 3 SECONDS. THIS TEST WAS PERFORMED IN TRIPLICATE. THEN 2 ML OF VENOUS BLOOD WAS OBTAINED FOR BLOOD ALCOHOL ANALYZING BY GC AS A REFERENCE METHOD.
THE RESULTS SHOWED THAT IN BREATH ALCOHOL ANALYSIS 104(52%) OF INDIVIDUALS HAD POSITIVE AND 96(48%) OF THEM HAD NEGATIVE RESULTS. IN COMPARISON IN GC METHODS 107(53.5%) OF INDIVIDUALS HAD POSITIVE AND 93(43.5%) OF THEM HAD NEGATIVE RESULTS. OUR STUDY SHOWED THAT THERE WERE NO FALSE POSITIVE RESULTS IN THIS METHOD AND THERE WERE 1.5% FALSE NEGATIVE RESULTS. THE CORRELATION COEFFICIENT WAS GREATER THAN 0.97 BETWEEN BREATH ALCOHOL CONCENTRATION (BRAC) AND BLOOD ALCOHOL CONCENTRATION (BAC).CONCLUSION: IN CONCLUSION THE BREATH ALCOHOL ANALYSIS IS A GOOD METHOD FOR QUALITATIVE AND QUANTITATIVE ANALYSIS IN FORENSIC MEDICINE CASES.

 
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