Paper Information

Title: 

THE EFFECT OF FICUS CARICA L. FRUIT AQUEOUS EXTRACT ON FORMALIN INDUCED PAIN IN THE MALE RAT PAW

Type: SPEECH
Author(s): MIRGHAZANFARI S.M.,ALAMEH H.,KAVANDI E.,SAJADI M.,ASHAYERI N.*,GHANBARPOUR F.,MOHAMMADZADEH Y.,KAMALINEZHAD MOHAMMAD,NASERI M.,PARVIZ M.
 
 *TRADITIONAL IRANIAN MEDICINE RESEARCH TEAM( TIM/RT), STUDENT'S SCIENTIFIC RESEARCH CENTER (SSRC), TEHRAN UNIVERSITY OF MEDICAL SCIENCES (TUMS)
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: Pain is one of the most common and important symptoms in many acute and chronic diseases in medicine. The common anti-nociceptive drugs used in Allopathic Medicine usually have some side effects, serious interactions with other drugs and sometimes high costs, but the medicinal herbs are effective, safe and cheap drugs usually. One of important medical plant in Traditional Iranian Medicine with analogous function as anti-nociceptive as defined in Allopathic Medicine is Ficus carica L..
Methods: Pain was established in rat paw as our testing grounds by subcutaneous injection of formalin. The severity of pain was assessed by formalin test every 15 seconds for one hour. The aqueous boiled Ficus extract in various doses (500, 1000, 2000 mg/kg) were compared with Sodium Salicylate (300mg/kg) and Distilled Water (DW) in intraperitoneal injections.
Results: There was no significant difference between groups that had been received extracts and control (DW) group (P>0.05).
Conclusion:
Based on our results, we conclude that   Ficus carica L. fruit aqueous extract in doses above, doesn't have any anti-nociceptive effect on Formalin induced pain in the male rat paw.

 
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