Paper Information

Title:  ANTI-INFLAMMATION EFFECTS OF ETHANOLIC EXTRACT OF SALVIA SCLAREA L. IN MICE
Type: SPEECH
Author(s): MORTEZAEI SEPIDEH S.A.*,EYDI AKRAM,MAZOUJI A.
 
 *DEPARTMENT OF BIOLOGY, SCIENCE & RESEARCH BRANCH, ISLAMIC AZAD UNIVERSITY, TEHRAN, IRAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Traditionally, plant medicines are used throughout the world for a range of pain complications. Plant drugs are frequently considered to be less toxic and free of side effects than synthetic ones. The study of such medicines might offer a natural key to alleviating of pain for the future. Many Salvia species and/or their essential oils are commonly used in the food, drug, cosmetic and perfumery industries. They are well known among people and widely used as flavourings or fragrances and for medicinal purposes in the several regions of the world. Recent studies reported analgesic, anti-inflammatory and antimicrobial effects of Salvia sclarea essential oil fractions and their relation to the chemical composition of the oil. The effects of the plant extracts on the CNS as well as on skeletal and smooth muscles have also been reported. To determine the anti-inflammation effects of Salvia sclarea, we investigated the effects of ethanolic extract of the plant in mice. The effect of the ethanolic extract against acute inflammation was studied by vascular permeability increased by xylene induced ear edema in mice. The ethanolic extract (1, 10, 50 and 100 mg/kg) were injected intraperitoneally. The control groups were administered saline as vehicle of ethanolic extract. In xylene ear edema, Salvia sclarea ethanolic extract showed significant activity in mice. The present data indicates that Salvia sclarea has anti-inflammation effect on mice and the plant should be considered in future therapeutic researches.

 
Keyword(s): 
 
Yearly Visit 8  
 
Latest on Blog
Enter SID Blog