Paper Information

Title:  STUDYING EFFECT OF STRESS ON WOUND HEALING IN RATS
Type: SPEECH
Author(s): DIANATI AJI BISHEH E.,KHATIBI TABATABAEI M.A.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: Stress could have considerable effect on physiological condition in all animals. As an index wound healing can be considered in order to evaluating these effects. Hearing stimuli are of these stressors that can affect wound healing period. In this research the effect of physiological stress on wound healing period is compared with psychological stress.
Animals and Method: 36 adult male Rats (Wistar Albino) (mean=150 gr) were injured by 2cm wound on their dorsal part of body, between shoulders and then were stitched. Wound was sterilized by Povidone iodine 10% and its pattern was drawn on transparent paper every day. Rats were divided into 3 mail groups: first group was faced with a 20db melody for 2 minute every two hours. Second group was faced with 70db melody, which is a tormentor for rats and the third group was faced with no hearing stimuli. In each group half of subjects were given electrical shock for 30second every 2 hour. Wound patterns on day 3, 7, 10 and 14 were selected for analysis.
Results: analyzing data with SPSS 11.5 had been shown: for animals which received both electrical and hearing shock wound healing period is significantly more than others. In addition each of electrical shock and hearing shock alone doesn't affect wound healing period more than the other one.
Discussion: stress can affect wound healing, but combination of physiological and psychological stress can intensify its effect.

 
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