Paper Information

Title: 

PHARMACOLOGICAL EFFECT OF SAFRANAL: A CONSTITUENT OF SAFFRON

Type: PAPER
Author(s): HOSSEINZADEH HOSSEIN*
 
 *PHARMACODYNAMY AND TOXICOLOGICAL DEPARTMENT, PHARMACEUTICAL RESEARCH CENTER, FACULTY OF PHARMACY, MASHHAD UNIVERSITY OF MEDICAL SCIENCES, MASHHAD
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Crocus sativus L. commonly known as saffron is a perennial stemless herb of the Iridaceae family and widely cultivated in Iran. Commercial saffron comprises the dried red stigma. Compounds considered pharmacologically active and important in saffron are volatile agents (e.g. safranal), bitter principles (e.g. picrocrocin) and dye materials (e.g. crocetin and its glycoside, crocin). Safranal is a monoterpene aldehyde, formed in saffron by hydrolysis from picrocrocin during drying and storage. It is the main essential volatile oil responsible for the characteristic saffron odor and aroma. In this study pharmacological and toxicological effects of safranal such as anticonvulsant, antioxidant, antianxiety and hypnotic, genoprotective, cerebral anti-ischemia and anticancer activities will be discussed.

 
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