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Paper Information

Journal:   JOURNAL OF RESEARCH IN DENTAL SCIENCES   spring 2019 , Volume 16 , Number 1 (59) ; Page(s) 1 To 12.

Histomorphometric Comparison of 2 types of FDBA and DFDBA bone powders manufactured by Hamanand Saz Baft Kish Company in treatment of defects in rabbit calvaria bone

Author(s):  Aghayan Shabnam*, ASGHARI AHMAD, MORTAZAVI PEJMAN, Ghashghai shahrzad
* Department of Periodontology, Faculty of Dentistry, Tehran Medical Sciences Azad University, Tehran, Iran
Background and aim: Allografts are a group of binding materials with various applications in restoration of osseous tissues. These materials are in two types: DFDBAs and FDBAs which have been evaluated and different reports are available regarding their properties. So we decided to launch a study and compare 2 types of FDBA and DFDBA osseous powders manufactured by Hamanand Saz Baft Kish Company and their application in restoration of calvaria bone damages in rabbits. Methods and Materials: The research performed on randomized clinical trial on 12 white rabbits. It was made 4 full 8 millimeter defects in calvaria bones in all rabbits. Then in group 1 we used DFDBA and in second group we used FDBA and the other groups were the positive and negative control groups. Within the 2 consecutive months (2, 4, 6, and 8 weeks) we sacrificed 3 rabbits for histologic and Histomorphometric analysis. Data were analyzed using Friedman and Mann-Whitney. We utilized SPSS ver: 20 software. Results: There were no statistically significant differences between groups FDBA and DFDBA in the filling status of the defect, inflammation and amount of resorption. At the end of 6 weeks in both groups, Inflammation also decreased in both groups from week 6. Foreign body reaction and complete remodeling of bone was not observed in both groups during the study period. Conclusions: Both of FDBA and DFDBA groups are the same in the rate of bone formation, inflammation and foreign body reaction and absorption.
Keyword(s): Calvaria,Allografts,Bone defect
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