Paper Information

Journal:   INTERNATIONAL JOURNAL OF MOLECULAR AND CLINICAL MICROBIOLOGY   2018 , Volume 8 , Number 1; Page(s) 903 To 911.
 
Paper: 

Evaluationof Mycoplasma muris and Mycoplasma pulmonis infections in Genital and Respiratory Tracts

 
 
Author(s):  ABEDINI FATEMEH*, Zinatizadeh Mohammad Reza, ASHTARI ABBAS, JAFARPOOR MOSTAFA, EBRAHIMI MOHAMMAD, Shokri Gholam Reza, FALLAHI Roozbeh
 
* Research and development Department, Razi Vaccine and Serum Research Institute, Agricultural Research, Educationand Extension Organization, Hesarak, Karaj, Alborz, Iran
 
Abstract: 
Mycoplasma pulmonis and muris infections have been associated with several diseases in conventionally housed laboratory rat and mice colonies. In naturally infected of mycoplasma pulmonis in mice and rat colonies, the respiratory organ appears to be the favored site of colonization; so, it was not surprising to see that infection spread from the site of urogenital tract to the respiratory tract. In this research, PPLO broth culture and polymerase chain reaction (PCR) assay was used to detect Mycoplasma pulmonis and muris contamination in mice strain NIH. A new species of Mycoplasma muris (MYMORazi) have been identified in the nasopharyngeal, lung and vaginal samples of mice strain NIH in Razi Vaccine and serum research institute. Despite using two pair's specific primers targeting 16SrRNA gene of Mycoplasma pulmonis, detection was failed in both organs. We propose that the Mycoplasma muris strain MYMO Razi can cause infection in both organs of mouse strain NIH without presence of Mycoplasma pulmonis.
 
Keyword(s): Mycoplasma muris,Mycoplasma pulmonis,Laboratory Mice,Vaginal Infection,Lung Infection
 
References: 
 
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