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Paper Information

Journal:   JOURNAL OF CHEMICAL HEALTH RISKS (JCHR)   2019 , Volume 9 , Number 1; Page(s) 69 To 74.

Evaluation of In-vitro Antimicrobial Activity of some Newly Synthesized2-amino-3-phenylsulfonyl-4-aryl-4H-benzo[h]chromens Derivatives

Author(s):  Manouchehri Farzaneh, Sadeghi Bahareh*, Najafi Farhood, Mosslemin Mohammad Hossein
* Department of Chemistry, Yazd Azad University, Yazd, Iran
In this study, some chromens derivatives were synthesized as mentioned in our previous report. The synthesized compounds were evaluated for their antibacterial effect against three different bacterial species, using Disk Diffusion Agar test and microdilution broth (MIC) method against the S. aureus, E. coli, P. aeruginosabacterias according to the National Committee for Clinical Laboratory Standards (NCCLS) recommendations. The results indicated that 4-nitro compound has considerable antibacterial activity against S. aureusbacteria. Moreover, compound 3-chloro has antibacterial properties againstE. coli standard strain and none of 4H-Chromens derivatives have antibacterial effect on P. aeruginosa strains.
Keyword(s): Antibacterial activity,4H-Chromens derivatives,Microdilutionbroth,Disk Diffusion Agar test
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