| Abstract:
Nowadays, millions of people around the world abused methamphetamine as drug in order to enjoy the day. With regard to the side and addictive effects of this drug, this study aimed to investigate the effects of Adagio and Allegro music on craving consumption in rats treated with methamphetamine. This experimental study was performed in Islamic Azad University of Marvdasht, Iran in 2016. Overall, 70 adult male rats were divided into control group (no treatment), sham (treated with a solvent) and 5 experimental groups receiving 1mg/kg methamphetamine influenced Adagio music, Allegro music, Adagio music with methamphetamine and Allegro music with methamphetamine. To assess craving consumption, conditioned place preference method was used. At the end, the data were evaluated using ANOVA and Tukey-test using SPSS-18. Significant differences of data at P≤ 0. 05 were observed from the data analysis. Using methamphetamine and Adagio music alone and with each other as well as Allegro music with methamphetamine resulted in a significant increase Conditioned Place Preference at P≤ 0/01 compared to the control group while the Allegro music alone showed no significant effect. Music and methamphetamine probably by stimulating oxytocin and dopamine systems of the brain caused to increase the conditioned place preference; therefore, likely Adagio music can be employed as a safe way to reduce craving consumption in abusers.
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