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Paper Information

Journal:   MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI)   2018 , Volume 32 , Number 1; Page(s) 0 To 0.
 
Paper: 

Citalopram and group psychotherapy in breast cancer patients: A randomized clinical trial

 
DOI: 

10.14196/mjiri.32.68

 
Author(s):  NIKBAKHSH NOVIN, MOUDI SUSSAN*, Alvarzandi Sara, Niazifar Maede, Farnoush Nazila, BIJANI ALI, MOUDI MARJAN
 
* Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
 
Abstract: 
Background: Depression is a common psychiatric disorder in breast cancer patients. This study was designed to evaluate the clinical efficacy of group psychotherapy on breast cancer patients with depressive disorder who took citalopram. Methods: This clinical trial was conducted on 40 breast cancer patients with depressive disorder. The control group received citalopram 20-40 mg/ day for 12 weeks and the intervention group participated in 8 sessions of group psychotherapy in addition to the same dose of citalopram. At the baseline and 3, 6, and 12 weeks after treatment, patients were followed-up. Treatment outcomes and quality of life were compared between the 2 groups. Results: Overall, the depression score of Hospital Anxiety and Depression Scale (HADS) at baseline with the mean of 11. 6± 1. 6 was signed in the range of clinical depression and after intervention it declined to 8. 8± 3. 6 (in the 3rd week), 7. 1± 3. 9 (6th week), and 5. 9± 4. 5 (12th week). Furthermore, HADS anxiety score at baseline with the mean of 12. 6± 2. 6 was signed in the range of clinical anxiety and after intervention it declined to 9. 1± 3. 0, 7. 3± 4. 1, and 6. 0± 4. 0, respectively. This improvement was significantly more in the combined therapy intervention group (p<0. 001). The mean score of quality of life based on WHO QOL-BREF questionnaire increased by 1. 85 fold in the case group, improved from 44. 09 to 81. 70, while the slight change was observed in the control group (p<0. 001). During the treatment, no significant adverse drug event was observed in the 2 groups (p>0. 05). Conclusion: Group psychotherapy has a significant effect on improving depression, anxiety, and quality of life in breast cancer patients.
 
Keyword(s): Breast cancer,Depression,Anxiety,Citalopram,Group psychotherapy
 
 
References: 
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Citations: 
 
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APA: Copy

NIKBAKHSH, N., & MOUDI, S., & Alvarzandi, S., & Niazifar, M., & Farnoush, N., & BIJANI, A., & MOUDI, M. (2018). Citalopram and group psychotherapy in breast cancer patients: A randomized clinical trial. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), 32(1), 0-0. https://www.sid.ir/en/journal/ViewPaper.aspx?id=667392



Vancouver: Copy

NIKBAKHSH NOVIN, MOUDI SUSSAN, Alvarzandi Sara, Niazifar Maede, Farnoush Nazila, BIJANI ALI, MOUDI MARJAN. Citalopram and group psychotherapy in breast cancer patients: A randomized clinical trial. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI). 2018 [cited 2021July29];32(1):0-0. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=667392



IEEE: Copy

NIKBAKHSH, N., MOUDI, S., Alvarzandi, S., Niazifar, M., Farnoush, N., BIJANI, A., MOUDI, M., 2018. Citalopram and group psychotherapy in breast cancer patients: A randomized clinical trial. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), [online] 32(1), pp.0-0. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=667392.



 
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