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Paper Information

Journal:   IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS   January-February 2019 , Volume 34 , Number 6 (92) #b00514; Page(s) 936 To 948.

Hematologic evaluation of the use of hydroalcoholic extract of baneh (Pistacia atlantica Desf. ) fruit in wistar white male rats

Author(s):  AZADBAKHT R., Jafarian Dehkordi m., KHANAMANI FALAHATIPOUR S.*, GHASEMI PIRBALOUTI A., Khanamani Falahatipour sodeh
* Physiology Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Baneh (Pistacia atlantica Desf. ) is a subspecies of pistachio and a native medicinal plant to Iran. Due to its diverse properties, Baneh is being applied in traditional medicine. The present experimental study was designed to evaluate the effects of the hydroalcoholic extract of Baneh on the hematological parameters of rats. Eighteen male Wistar rats weighing 170-240 gr were divided into three six-member groups. Oral administration in groups 1 to 3 was performed by gavage with 200 mg/kg bw of the extract, 400 mg/kg bw of the extract and distilled water (control group) for 30 days, respectively. Then, blood samples were taken from the heart of rats and hematological tests were done on the samples. The obtained data were analyzed using SPSS software version 21, one-way ANOVA, and Tukey tests. Administration of different concentrations of hydroalcoholic extract significantly increased the number of red blood cells (RBC), white blood cells (WBC), and hemoglobin (Hb) concentration in test groups compared with the control group. In addition, the average volume of red blood cells (MCV) decreased in the test group receiving 200mg/kg bw compared with the control group. However, it has no effect on other blood parameters (P<0. 05). The Baneh extract increased the number of RBCs and Hb concentration that can be due to the increase in the hematopoiesis process. Moreover, increased WBC after treatment with Baneh extract can enhance the body resistance against pathogenic agents.
Keyword(s): (Pistacia atlantica Desf.),traditional medicine,oral administration,hematological tests
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