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Paper Information

Journal:   UROLOGY JOURNAL   March-April 2019 , Volume 16 , Number 2; Page(s) 145 To 151.
 
Paper: 

Long-term Changes in Renal Function, Blood Electrolyte Levels, and Nutritional Indices After Radical Cystectomy and Ileal Conduit in Patients with Bladder Cancer

 
DOI: 

10.22037/uj.v0i0.4531

 
Author(s):  Miyake Makito*, Owari Takuya, Tomizawa Mitsuru, Matsui Masaru, Nishibayashi Naoko, Iida Kota, Onishi Kenta, Hori Shunta, Morizawa Yosuke, Gotoh Daisuke, Itami Yoshitaka, Nakai Yasushi, Inoue Takeshi, Anai Satoshi, Torimoto Kazumasa, Aoki Katsuya, Tanaka Nobumichi, Fujimoto Kiyohide
 
* Department of Urology, Nara Medical University, 840 Shijo-cho, Nara 634-8522, Japan
 
Abstract: 
Purpose: To assess the long-term changes in renal function, blood electrolyte levels, and nutritional indices after radical cystectomy and ileal conduit in patients with bladder cancer. Patients and Methods: In 129 patients who underwent radical cystectomy and ileal conduit, we evaluated clinicopathologic features, complications, and the change in the estimated glomerular filtration rate (eGFR) from baseline to 1, 2, 3, 4, 5, and 10 years postoperatively. Two nutritional indices, the geriatric nutritional risk index (GNRI) and prognostic nutrition index (PNI), were calculated with laboratory tests. Results: In the ileal conduit group, a parastromal hernia was observed in 10% of patients, whereas 13% had an ureteroenteric anastomotic stricture, which was associated with greater decline in the eGFR postoperatively. The first 5 year-decline in the eGFR was 1. 74 mL/min/1. 73 m2/year. The levels of only potassium showed a significant increase at 1 year postoperatively (mean: 4. 34 mEq/L) and remained high compared with the baseline (4. 14 mEq/L). Evaluation of the nutritional indices demonstrated that the GNRI, and not PNI, showed a significant, transient increase from 1 to 4 years (range: 108− 110) postoperatively compared with the baseline (105). Conclusion: The first 5 year-decline was much higher than that among Japanese individuals who participated in an annual health examination program. Further research should be performed to identify an appropriate strategy for selecting the suitable type of urinary diversion and postoperative nutritional interventions to improve the clinical outcome of patients with bladder cancer.
 
Keyword(s): Urinary Bladder Neoplasms,Cystectomy,Urinary Diversion,Kidney Failure,Chronic,Electrolyte,Nutritional Status
 
 
References: 
 
+ Click to Cite.
APA: Copy

Miyake, M., & Owari, T., & Tomizawa, M., & Matsui, M., & Nishibayashi, N., & Iida, K., & Onishi, K., & Hori, S., & Morizawa, Y., & Gotoh, D., & Itami, Y., & Nakai, Y., & Inoue, T., & Anai, S., & Torimoto, K., & Aoki, K., & Tanaka, N., & Fujimoto, K. (2019). Long-term Changes in Renal Function, Blood Electrolyte Levels, and Nutritional Indices After Radical Cystectomy and Ileal Conduit in Patients with Bladder Cancer. UROLOGY JOURNAL, 16(2), 145-151. https://www.sid.ir/en/journal/ViewPaper.aspx?id=665787



Vancouver: Copy

Miyake Makito, Owari Takuya, Tomizawa Mitsuru, Matsui Masaru, Nishibayashi Naoko, Iida Kota, Onishi Kenta, Hori Shunta, Morizawa Yosuke, Gotoh Daisuke, Itami Yoshitaka, Nakai Yasushi, Inoue Takeshi, Anai Satoshi, Torimoto Kazumasa, Aoki Katsuya, Tanaka Nobumichi, Fujimoto Kiyohide. Long-term Changes in Renal Function, Blood Electrolyte Levels, and Nutritional Indices After Radical Cystectomy and Ileal Conduit in Patients with Bladder Cancer. UROLOGY JOURNAL. 2019 [cited 2021May18];16(2):145-151. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=665787



IEEE: Copy

Miyake, M., Owari, T., Tomizawa, M., Matsui, M., Nishibayashi, N., Iida, K., Onishi, K., Hori, S., Morizawa, Y., Gotoh, D., Itami, Y., Nakai, Y., Inoue, T., Anai, S., Torimoto, K., Aoki, K., Tanaka, N., Fujimoto, K., 2019. Long-term Changes in Renal Function, Blood Electrolyte Levels, and Nutritional Indices After Radical Cystectomy and Ileal Conduit in Patients with Bladder Cancer. UROLOGY JOURNAL, [online] 16(2), pp.145-151. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=665787.



 
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