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Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   November 2018 , Volume 16 , Number 11; Page(s) 719 To 722.
 
Paper: 

Investigation of anti-mullerian hormone (AMH) level and ovarian response in infertile women with endometriosis in IVF cycles

 
 
Author(s):  SAFDARIAN LEILI, Ghalandarpoor Attar Seyedeh Noushin, ALEYASIN ASHRAF, AGHAHOSSEINI MARZIEH, Sadaf Sarfjoo Fateme, Hosseinimousa Sedigheh*
 
* Department of Obstetrics and Gynecology, Infertility Unit, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Postal Cod: 1411713135
 
Abstract: 
Background: Endometriosis, can cause ovarian conflict and reduced ovarian reserve that could lead to lower response to assisted reproductive techniques Objective: Current study was conducted to determine the association between level of anti-mullerian hormone (AMH) and the infertility treatment outcomes in infertile females with endometriosis versus the non-endometriosis infertile subject. Materials and Methods: In this case-control study, 64 infertile females who referred to Shariati Hospital from April 2015 to November 2017 were enrolled. They were divided in two groups of 32 patients (endometriosis and non-endometriosis women). The anti-mullerian hormone level among all subjects was determined, treatment outcomes were evaluated and association between these factors was assessed. Results: It was seen that the anti-mullerian hormone (p=0. 06), the number of retrieved oocytes (p=0. 7) and embryos (p=0. 7), implantation rate (p=0. 6) and clinical pregnancy rate (p=0. 9) were similar between two groups. In patients with stage 3 or 4 endometriosis who had lower serum AMH level significantly (p=0. 001) less oocytes were retrieved (p=0. 001) and less transferrable embryos (p=0. 03) were achieved. However, implantation and pregnancy rates did not differ (p=0. 7) (p=0. 6). Conclusion: Totally, according to the obtained results, it may be concluded that ovarian reserve has more significant role in predicting infertility treatment outcome rather than receptive endometrium.
 
Keyword(s): Endometriosis,Infertility,Anti-mullerian hormone
 
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