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Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   November 2018 , Volume 16 , Number 11; Page(s) 697 To 702.
 
Paper: 

The effect of inflammatory diseases associated with opportunistic urogenital infection on the hormonal function of the female reproductive system

 
 
Author(s):  Rasimovich Abdrakhmanov Azat*, Mindrakhmanovich Abdrakhmanov Rasim
 
* Reproductive Health Research Center, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia
 
Abstract: 
Background: Sexually transmitted infections play a great role in formation of inflammatory diseases of female urogenital system. These diseases can cause a decrease in the level of female sex hormones, as well as the ratio of estrogens and androgens. Objective: To determine changes in the state of sex hormones in women with inflammatory diseases of ovaries associated with opportunistic urogenital flora. Materials and Methods: 136 women aged 18-39 yr participated in this crosssectional clinical study. They were examined with the use of a complex of clinical, laboratory and instrumental methods of examination. The patients with confirmed diagnosis of inflammatory disease of reproductive system associated with opportunistic urogenital infection have been under blood analysis to reveal the concentration of follicle-stimulating hormone, luteinizing hormone, and estrogens. Results: After the treatment the functional capacity of ovary significantly increased, proved by a corresponding increase in the concentration of estradiol hormone in blood serum in all phases of menstrual cycle. According to estradiol in follicular phase its concentration was increased from 421. 8± 10. 8 nmol/L to 581. 3± 10. 2 nmol/L. The elevation in the ratio of estradiol/testosterone hormones in blood serum also is demonstrated. Conclusion: Inflammatory diseases associated with opportunistic urogenital infection is responsible for a decrease of female sex hormones and the ratio of estrogens and androgens.
 
Keyword(s): Urogenital infection,Pelvic inflammatory disease,Reproductive system,Estradiol,Infertility
 
References: 
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