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Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   MAY 2019 , Volume 17 , Number 5; Page(s) 375 To 376.
 
Paper: 

Prothrombin gene mutations do not cause recurrent pregnancy loss in the Indian population (Letter to Editor)

 
 
Author(s):  Reddy Ravindranath, Mutreja Deepti, Mukhopadhyay Indrani, Moorchung Nikhil*
 
* Department of Pathology, Command Hospital Air Force, AGRAM Post, Cambridge Layout, Bangalore 560007, India, Postal Code: 560001
 
Abstract: 
Dear Editor,
As defined by the American Society of Reproductive Medicine, recurrent miscarriage or recurrent pregnancy loss is defined as two or more failed pregnancies. (1). There are various causes for RPL and yet, in about 40% of cases, no cause can be identified after extensive investigation. It is believed that inherited and acquired thrombophilia like Protein C/S deficiency and genetic mutations in the Factor V and the Prothrombin gene maybe a cause of RPL (2). There is a significant association between the Prothrombin G2021M mutation (PTG) with RPL which has been shown by numerous other studies (3). The data with respect to PTG G20210A mutations and its association with RPL is scant in Indian population. In this study, we evaluated a total of 56 women in this point prevalence cross-sectional study. The sample size was determined on the basis of the number of women attending the antenatal OPD (n-10000), the RPL prevalence in the general population (1%), and the Confidence Interval (5%). The sample size was calculated by the EPI Info software. The sample size was calculated as 38.
 
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APA: Copy

Reddy, R., & Mutreja, D., & Mukhopadhyay, I., & Moorchung, N. (2019). Prothrombin gene mutations do not cause recurrent pregnancy loss in the Indian population (Letter to Editor). INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 17(5), 375-376. https://www.sid.ir/en/journal/ViewPaper.aspx?id=665298



Vancouver: Copy

Reddy Ravindranath, Mutreja Deepti, Mukhopadhyay Indrani, Moorchung Nikhil. Prothrombin gene mutations do not cause recurrent pregnancy loss in the Indian population (Letter to Editor). INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE). 2019 [cited 2021July31];17(5):375-376. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=665298



IEEE: Copy

Reddy, R., Mutreja, D., Mukhopadhyay, I., Moorchung, N., 2019. Prothrombin gene mutations do not cause recurrent pregnancy loss in the Indian population (Letter to Editor). INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), [online] 17(5), pp.375-376. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=665298.



 
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