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Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   October 2016 , Volume 14 , Number 10; Page(s) 625 To 628.
 
Paper: 

Effects of autologous platelet-rich plasma on implantation and pregnancy in repeated implantation failure: A pilot study

 
 
Author(s):  Nazari Leila*, SALEHPOUR SAGHAR, Hoseini Sedighe, Zadehmodarres Shahrzad, Ajori Ladan
 
* Department of Obstetrics and Gynecology, Preventive Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
 
Abstract: 
Background: Repeated implantation failure (RIF) is a major challenge in reproductive medicine and despite several methods that have been described for management, there is little consensus on the most effective one. Objective: This study was conducted to evaluate the effectiveness of platelet-rich plasma in improvement of pregnancy rate in RIF patients. Materials and Methods: Twenty women with a history of RIF who were candidates for frozen-thawed embryo transfer were recruited in this study. Intrauterine infusion of 0. 5 ml of platelet-rich plasma that contained platelet 4-5 times more than peripheral blood sample was performed 48 hrs before blastocyst transfer. Results: Eighteen participants were pregnant with one early miscarriage and one molar pregnancy. Sixteen clinical pregnancies were recorded and their pregnancies are ongoing. Conclusion: According to this study, it seems that platelet-rich plasma is effective in improvement of pregnancy outcome in RIF patients.
 
Keyword(s): Platelet-rich plasma,Implantation,Fertilization in Vitro,Pregnancy rate,Repeated implantation failure
 
 
References: 
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Citations: 
 
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APA: Copy

Nazari, L., & SALEHPOUR, S., & Hoseini, S., & ZADEHMODARRES, S., & Ajori, L. (2016). Effects of autologous platelet-rich plasma on implantation and pregnancy in repeated implantation failure: A pilot study. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 14(10), 625-628. https://www.sid.ir/en/journal/ViewPaper.aspx?id=664942



Vancouver: Copy

Nazari Leila, SALEHPOUR SAGHAR, Hoseini Sedighe, ZADEHMODARRES SHAHRZAD, Ajori Ladan. Effects of autologous platelet-rich plasma on implantation and pregnancy in repeated implantation failure: A pilot study. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE). 2016 [cited 2021June23];14(10):625-628. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=664942



IEEE: Copy

Nazari, L., SALEHPOUR, S., Hoseini, S., ZADEHMODARRES, S., Ajori, L., 2016. Effects of autologous platelet-rich plasma on implantation and pregnancy in repeated implantation failure: A pilot study. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), [online] 14(10), pp.625-628. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=664942.



 
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