Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   june 2017 , Volume 15 , Number 6; Page(s) 345 To 350.
 
Paper: 

Evaluation of vitamin D status and its correlation with oxidative stress markers in women with polycystic ovary syndrome

 
 
Author(s):  Rahsepar Maryam, MAHJOUB SOLEIMAN*, ESMAEILZADEH SEDIGHEH, Kanafchian Maryam, GHASEMI MARYAM
 
* FATEMEH ZAHRA INFERTILITY AND REPRODUCTIVE HEALTH RESEARCH CENTER, BABOL UNIVERSITY OF MEDICAL SCIENCES, BABOL, IRAN
 
Abstract: 
Background: There is little evidence about antioxidant properties of vitamin D. Recent studies suggest that oxidative stress may play a major role in the pathophysiology of polycystic ovary syndrome (PCOS), but the association of vitamin D with oxidative stress is still not known in PCOS. Objective: The goal of the present study was to evaluate the correlation between serum 25-hydroxy vitamin D and oxidative stress markers in PCOS group compared to control group. Materials and Methods: 60 PCOS women (20-40 yr old) and 90 healthy women as control group were participated in this case-control study. Fasting serum level of 25-hydroxy vitamin D 25(OH) D, glucose, insulin, calcium, malondialdehyde (MDA), protein carbonyl (PC), also homeostasis model assessment for insulin resistance (HOMA-IR) and fasting glucose to insulin ratio (FGIR) were measured. Results: It was found that the mean of serum 25(OH)D was lower in the PCOS group (10. 76± 4. 17) than in the control group (12. 07± 6. 26) but this difference was not statistically significant (p=0. 125). Fasting insulin, HOMA-IR and MDA were significantly higher in the PCOS patients as compared to the controls, whereas PC level did not differ for the two groups (p=0. 156). No significant correlations were found between 25(OH) D levels and oxidative stress markers (MDA and PC). Conclusion: The findings indicated no significant differences in the serum 25(OH) D levels between the PCOS patients and the matched controls. Also, no correlation was found between the serum vitamin D levels and oxidative stress markers in both groups.
 
Keyword(s): Polycystic ovary syndrome,Vitamin D,Oxidative stress,Malondialdehyde
 
 
References: 
  • Not Registered.
  •  
  •  
 
Citations: 
 
+ Click to Cite.
APA: Copy

Rahsepar, M., & MAHJOUB, S., & ESMAEILZADEH, S., & Kanafchian, M., & GHASEMI, M. (2017). Evaluation of vitamin D status and its correlation with oxidative stress markers in women with polycystic ovary syndrome. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 15(6), 345-350. https://www.sid.ir/en/journal/ViewPaper.aspx?id=664775



Vancouver: Copy

Rahsepar Maryam, MAHJOUB SOLEIMAN, ESMAEILZADEH SEDIGHEH, Kanafchian Maryam, GHASEMI MARYAM. Evaluation of vitamin D status and its correlation with oxidative stress markers in women with polycystic ovary syndrome. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE). 2017 [cited 2021June12];15(6):345-350. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=664775



IEEE: Copy

Rahsepar, M., MAHJOUB, S., ESMAEILZADEH, S., Kanafchian, M., GHASEMI, M., 2017. Evaluation of vitamin D status and its correlation with oxidative stress markers in women with polycystic ovary syndrome. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), [online] 15(6), pp.345-350. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=664775.



 
  pdf-File
Yearly Visit 39
 
 
Latest on Blog
Enter SID Blog