Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   june 2017 , Volume 15 , Number 6; Page(s) 345 To 350.
 
Paper: 

Evaluation of vitamin D status and its correlation with oxidative stress markers in women with polycystic ovary syndrome

 
 
Author(s):  Rahsepar Maryam, MAHJOUB SOLEIMAN*, ESMAEILZADEH SEDIGHEH, Kanafchian Maryam, GHASEMI MARYAM
 
* FATEMEH ZAHRA INFERTILITY AND REPRODUCTIVE HEALTH RESEARCH CENTER, BABOL UNIVERSITY OF MEDICAL SCIENCES, BABOL, IRAN
 
Abstract: 
Background: There is little evidence about antioxidant properties of vitamin D. Recent studies suggest that oxidative stress may play a major role in the pathophysiology of polycystic ovary syndrome (PCOS), but the association of vitamin D with oxidative stress is still not known in PCOS. Objective: The goal of the present study was to evaluate the correlation between serum 25-hydroxy vitamin D and oxidative stress markers in PCOS group compared to control group. Materials and Methods: 60 PCOS women (20-40 yr old) and 90 healthy women as control group were participated in this case-control study. Fasting serum level of 25-hydroxy vitamin D 25(OH) D, glucose, insulin, calcium, malondialdehyde (MDA), protein carbonyl (PC), also homeostasis model assessment for insulin resistance (HOMA-IR) and fasting glucose to insulin ratio (FGIR) were measured. Results: It was found that the mean of serum 25(OH)D was lower in the PCOS group (10. 76± 4. 17) than in the control group (12. 07± 6. 26) but this difference was not statistically significant (p=0. 125). Fasting insulin, HOMA-IR and MDA were significantly higher in the PCOS patients as compared to the controls, whereas PC level did not differ for the two groups (p=0. 156). No significant correlations were found between 25(OH) D levels and oxidative stress markers (MDA and PC). Conclusion: The findings indicated no significant differences in the serum 25(OH) D levels between the PCOS patients and the matched controls. Also, no correlation was found between the serum vitamin D levels and oxidative stress markers in both groups.
 
Keyword(s): Polycystic ovary syndrome,Vitamin D,Oxidative stress,Malondialdehyde
 
References: 
  • ندارد
 
  pdf-File tarjomyar Yearly Visit 0
 
Latest on Blog
Enter SID Blog