Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   ARCHIVES OF IRANIAN MEDICINE   January 2019 , Volume 22 , Number 1; Page(s) 24 To 31.
 
Paper: 

Reference Values for Serum Lipid Profiles in Iranian Adults: Tehran Lipid and Glucose Study

 
 
Author(s):  RAHMANI MARYAM, JEDDI SAJAD, Ghanbari Mahboubeh, MOMENAN AMIR ABBAS, AZIZI FEREIDOUN, GHASEMI ASGHAR*
 
* Endocrine Physiology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
 
Abstract: 
Background: Lipid abnormalities are major risk factors for cardiovascular diseases. In addition to age and sex, other variables can affect serum lipid levels, warranting the determination of population-specific reference values. This study aimed to determine age-and sex-specific reference values for serum total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and triglycerides (TG) in healthy Tehranian adults. Methods: TC, TG, and HDL-C were measured using the enzymatic colorimetric method and the Friedewald equation (LDL-C = TC − HDL-C − TG/5) was used to calculate LDL-C concentrations in individuals with TG <400 mg/dL. After applying the exclusion criteria, 1147 participants (548 men and 599 women) aged ≥ 20 years were included. For determining reference values, the International Federation of Clinical Chemistry guidelines (non-parametric method) and the robust method were used for sample sizes ≥ 120 and <120, respectively. Results: Reference values for serum TC, LDL-C, HDL-C, and TG were 121. 0– 261. 0, 54. 1– 175. 2, 30. 9– 71. 9, and 46. 9– 301. 2 mg/dL in men and 117. 8– 235. 9, 49. 9– 160. 9, 36. 0– 83. 9, and 38. 1– 184. 2 mg/dL in women, respectively. All parameters except HDL-C were higher in men than women and showed an increasing trend with age. Conclusion: Reference values for serum TC, LDL-C, HDL-C, and TG in healthy Tehranian adults were determined, and these values could provide the basis for better decision making in both prevention and clinical settings.
 
Keyword(s): Cholesterol,Coronary heart disease,Lipid,Reference values,Triglycerides
 
References: 
 
  pdf-File tarjomyar Yearly Visit 73
 
Latest on Blog
Enter SID Blog