The purpose of this study was to compare the effectiveness of Massage Therapy, Alexander Technique, and Dohsa-hou treatment on happiness, social adjustment, hope, mental health and quality of life in the elderly with Parkinson's disease. The research was quasi-experimental. The statistical population of this study was all the elderly with Parkinson' s disease who referred to clinics in Isfahan in 2015. Among them, 42 patients were selected through convenience sampling and were divided randomly to three groups including Massage Therapy (n=14), Alexander Technique (n=14), and Dohsa-hou (n=14) group. Oxford Happiness Inventory (OHI) (Argyle, 2013), Social Adjustment Scale (Hosseini & Moghtader, 2009), Adult Hope Scale (Snyder, Irving & Anderson, 1991), General Health Questionnaire (Kaviani, Mousavi & Mohit, 2001), and Word Health Organization Quality of Life Questionnaire (WHOQOL Group, 1994), were used as research instruments. Data were analyzed by Multivariate analysis of covariance (MANCOVA). The results showed that there is no significant difference between the effectiveness of three interventions on dependent variables in the post-test stage, but in the follow -up stage, Dohsa-hou had more influence on happiness than other interventions of the research. Based on the results of the present study, in long term Dohsa-hou treatment in comparison to other similar treatments, can be considered as a more effective therapy for happiness.