Paper Information

Journal:   INTERNATIONAL JOURNAL OF PEDIATRICS   JUNE 2018 , Volume 6 , Number 6 (54); Page(s) 7769 To 7780.
 
Paper: 

EVALUATION OF SERUM NT-PRO BRAIN NATRIURETIC PEPTIDE LEVELS IN NEONATES WITH RESPIRATORY DISTRESS

 
 
Author(s):  NOORI NOORMOHAMMAD, YAZDANPARAST AMER, NAKHAEI MOGHADAM MARYAM, TEIMOORI ALIREZA*
 
* CHILDREN AND ADOLESCENT HEALTH RESEARCH CENTER, RESISTANT TUBERCULOSIS INSTITUTE, ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES, ZAHEDAN, IRAN
 
Abstract: 

Background Respiratory Distress (RD) is a life-threatening respiratory failure. This study aimed to evaluate the diagnostic value of N-terminal prohormone of brain natriuretic peptide (NT-pro-BNP) in distinguishing respiratory and heart diseases in neonates.
Materials and Methods Hundred fifty neonates aged 2-3 days randomly collected from those who hospitalized in the related ward of the Ali Ebne Abitaleb Hospital, Zahedan, Iran. After sampling 2ml blood from venipuncture by trained nurse in the related ward separated serums performed in a laboratory. Then, 250
ml of the patients’ serum was isolated to assess NT- pro-BNP level using ELISA kit (USA). Data were analyzed using SPSS software version 20.0 with considering of P<0.05.
Results Mean of NT-pro-BNP in respiratory, Acyanotic, cyanotic and controls were 386.22±208.82, 384.83±183.74, 372.23±143.04, and 161.70- ± 121.2, respectively. Weight, height and head circumference had different mean ranks for respiratory, Acyanotic, cyanotic and healthy groups, respectively (P<0.05).
Conclusion According to the results, despite of some reports, NT-proBNP is good biomarker to determine differentiate between cardiac and respiratory during neonate.

 
Keyword(s): CONGENITAL HEART DISEASE, NEONATES, NT- PRO-BNP, RESPIRATORY
 
References: 
  • ندارد
 
  pdf-File tarjomyar Yearly Visit 46
 
Latest on Blog
Enter SID Blog