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Paper Information

Journal:   INTERNATIONAL JOURNAL OF PEDIATRICS   MAY 2018 , Volume 6 , Number 5 (53); Page(s) 7651 To 7652.
 
Paper: 

PREVALENCE OF ADENOVIRUS AMONG CHILDREN WITH GASTROENTERITIS/ DIARRHEA IN WARRI, DELTA STATE, SOUTHERN, NIGERIA

 
 
Author(s):  QUADRI BOLATITO WILLIAM JOHNSON*, OSAZUWA FAVOUR
 
* EPIDEMIOLOGIST, GLOBAL HEPATITIS INITIATIVE NIGERIA (GHIN), NIGERIA
 
Abstract: 

Dear Editor-in-Chief, Adenovirus are double stranded DNA viruses, known to be capable of causing various kind of illnesses from mild respiratory infections in young children (known as thecommon cold) to life-threatening multi-organ disease in people with a weakened immune system (1). In humans, there are 57 accepted human adenovirus types (HAdV-1 to 57) in seven species (Human adenovirus A to G) (1). Adenovirus is currently recognized as one of the viral causes of diarrhea/gastroenteritis among children (2), with types 40 and 41 predominating as common causes of gastroenteritis, especially in children under the age of two year-old (2). This letter reports the preliminary investigation on the prevalence of Adenovirus among children (under-5 years old) presenting with diarrhea/gastroenteritis at the pediatric outpatients of Central Hospital, Warri, a tertiary health care facility in Delta State, South-South, Nigeria. Ethical approval was provided by the Delta Hospitals Management board in the letter CHW/VOL 1/17/14. This study included a total of 100 subjects, 75 children with clinical diarrhea/gastroenteritis, and 25 age and sex matched healthy children as controls. Adenovirus was detected in fecal specimens of subjects using a rapid lateral flow immunochromatographic assay kit (Gastro Vir-Strip, Coris Bioconcept, Belgium).
Data on demographics and social characteristics where obtained with the aid of a self-administered questionnaire. The prevalence of Adenovirus was 14.7% (11/75 patients); Adenovirus was not detected among the control subjects. The prevalence of Adenovirus was more in Males than females, but this were not significantly different (odds ratio [OR]: 0.9592, 95% confidence interval [CI]: 0.2576, 3.5712). Adenovirus prevalence was also independent of age (P=0.9045). The prevalence of Adenovirus in this locality is quite close to the prevalence of 18%, and 19.3% in neighboring states of Ondo and Edo, Nigeria (3, 4), but less than 23% among children in Northwestern, Nigeria (5). In conclusion, the prevalence of Adenovirus was high; and was independent of age and gender. There is need for routine screening of Adenovirus among children with gastroenteritis/diarrhea in our locality irrespective of age or gender. Further studies are needed to provide information on prevalent Adenovirus subtypes and genotypes in this study location.

 
Keyword(s): ADENOVIRUS, CHILDREN, DIARRHEA, NIGERIA, PREVALENCE
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

QUADRI BOLATITO, W., & OSAZUWA, F. (2018). PREVALENCE OF ADENOVIRUS AMONG CHILDREN WITH GASTROENTERITIS/ DIARRHEA IN WARRI, DELTA STATE, SOUTHERN, NIGERIA. INTERNATIONAL JOURNAL OF PEDIATRICS, 6(5 (53)), 7651-7652. https://www.sid.ir/en/journal/ViewPaper.aspx?id=572899



Vancouver: Copy

QUADRI BOLATITO WILLIAM JOHNSON, OSAZUWA FAVOUR. PREVALENCE OF ADENOVIRUS AMONG CHILDREN WITH GASTROENTERITIS/ DIARRHEA IN WARRI, DELTA STATE, SOUTHERN, NIGERIA. INTERNATIONAL JOURNAL OF PEDIATRICS. 2018 [cited 2021July25];6(5 (53)):7651-7652. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=572899



IEEE: Copy

QUADRI BOLATITO, W., OSAZUWA, F., 2018. PREVALENCE OF ADENOVIRUS AMONG CHILDREN WITH GASTROENTERITIS/ DIARRHEA IN WARRI, DELTA STATE, SOUTHERN, NIGERIA. INTERNATIONAL JOURNAL OF PEDIATRICS, [online] 6(5 (53)), pp.7651-7652. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=572899.



 
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