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Paper Information

Journal:   WORLD JOURNAL OF PLASTIC SURGERY   SEPTEMBER 2016 , Volume 5 , Number 3; Page(s) 280 To 286.
 
Paper: 

COMPARISON OF THE ANALGESIC EFFECT OF PARACETAMOL AND MAGNESIUM SULFATE DURING SURGERIES

 
 
Author(s):  KALANI NAVID, SANIE MOHAMMAD SADEGH*, ZABETIAN HASAN, RADMEHR MOHAMMAD, SAHRAEI REZA, KARGAR JAHROMI HOSSEIN, ZARE MARZOUNI HADI
 
* DEPARTMENT OF ANAESTHESIOLOGY, JAHROM UNIVERSITY OF MEDICAL SCIENCES, JAHROM, IRAN
 
Abstract: 

BACKGROUND
New drugs are increasingly used to induce analgesia during surgeries. This study compared the analgesic effects of paracetamol and magnesium sulfate.
METHODS
Sixty patients with American Society of Anesthesiologists (ASA) class I or II patients who were candidates for surgery of the lower limbs were randomly divided into three equal groups who were age and gender matched. Group 1 received paracetamol, and group 2, the magnesium sulfate during surgery and group 3 as the control. Pain intensities were measured and recorded using the Visual Analog Scale before surgery, in the recovery room, and 6, 12, and 18 hours after surgery.
RESULTS
Pain intensities (7.10, 5.80, and 4.10) were higher in the control group; 6, 12, and 18 hours after surgery compared to the paracetamol (6.45, 4.15, 2.50) and the magnesium groups (7.25, 4.55, and 2.05), but the difference was not statistically significant.
CONCLUSION
Paracetamol and magnesium sulfate were shown to have postoperative analgesic effects and reduce the quantity of narcotic use after surgery.

 
Keyword(s): PARACETAMOL, MAGNESIUM SULFATE, ANALGESIA, PAIN, LIMB
 
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