Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   INTERNATIONAL JOURNAL OF PEDIATRICS   APRIL 2018 , Volume 6 , Number 4 (52); Page(s) 7495 To 7499.
 
Paper: 

TWO CASE REPORTS OF NETHERTON SYNDROME: HAIR SHAFT EXAMINATION IS KNOWN AS A DIAGNOSTIC TEST

 
 
Author(s):  MALEKIANTAGHI ARMEN, KHODADAD AHMAD, MODARESISARYAZDI VAJIHEH, EFTEKHARI KAMBIZ*
 
* PEDIATRIC DEPARTMENT, BAHRAMI CHILDREN’S HOSPITAL, KIAEE STREET, TEHRAN IRAN, POSTAL CODE: 16417-44991
 
Abstract: 

Background: Netherton syndrome is a rare autosomal recessive disorder consisting of ichthyosis form dermatosis, hair shaft abnormalities and an atopic diathesis that presents as widespread erythematous skin. The aim of these reports is emphasis on the importance of the examination of hair as a diagnose route.
Case presentation Case 1: A 6 months old boy with respiratory distress and severe erythematous itchy scaling lesions. He had been under treatment of topical steroid without improvement. Case 2: A 28 days old boy admitted for failure to weight gain with presentation of extensive dermatologic involvement, severe dehydration and respiratory distress.
Results: Examination of hair under light microscopy revealed trichorrhexis invaginata, highly suggestive for Netherton syndrome.
Conclusion: In countries where access to genetic diagnostic tests is difficult, hair examination is the best and inexpensive definitive diagnostic method compared to the expensive genetic tests for diagnose of Netherton syndrome.

 
Keyword(s): HAIR, ICHTHYOSIFORM DERMATOSIS, NETHERTON SYNDROME, TRICHORRHEXIS
 
References: 
  • ندارد
 
  pdf-File tarjomyar Yearly Visit 55
 
Latest on Blog
Enter SID Blog