Paper Information

Journal:   INTERNATIONAL JOURNAL OF PEDIATRICS   FEBRUARY 2018 , Volume 6 , Number 2 (50); Page(s) 7117 To 7127.
 
Paper: 

VITAMIN D STATUS IN PREGNANT WOMEN AND THEIR NEWBORNS IN KARAJ: A CROSS-SECTIONAL STUDY IN IRAN

 
 
Author(s):  HOSSEINZADEH ZHALEH, KAZEMIAN MOHAMMAD, MASHAK BANAFSHEH, TORKMANDI HOJJAT, BADFAR GHOLAMREZA*
 
* DEPARTMENT OF PEDIATRICS, BEHBAHAN SCHOOL OF MEDICINE, AHVAZ JUNDISHAPOUR UNIVERSITY OF MEDICAL SCIENCE, BEHBAHAN, IRAN
 
Abstract: 

Background Pregnant women and newborns are at risk of vitamin D deficiency. This study aimed to determine the vitamin D status in pregnant women and their newborns in Karaj, Iran.
Materials and Methods This cross-sectional study was conducted from March 2014 to October 2015. A total of 151 pregnant women and 154 newborns (three twin cases) were included in the study. After obtaining 5 ml venous blood samples from mothers and 5 ml blood from the umbilical cord of newborns, 25-hydroxy vitamin D [25 (OH) D] was measured by ELISA method. Serum level of 25 (OH) D below 20 ng/ml was considered deficiency, 21-29 ng/ml wasconsidered insufficient and 30-100 ng/ml was considered sufficient. Data were analyzed using SPSS software version 20.0.
Results The prevalence of vitamin D deficiency and its insufficiency was 93.5% and 6.5% for pregnant women, 94.2% and 3.9% for newborns, respectively. The mean 25 (OH) D concentration in pregnant women and newborns was estimated to be 10.649±5.967 ng/ml and 10.574±6.280 ng/ml, respectively. There was a significant correlation between the mean 25 (OH) D concentration in mothers and their newborns (r=0.913 and p<0.001); 92.9% of mothers and their newborns had vitamin D deficiency simultaneously.
Conclusion The results of this study showed that overall prevalence of vitamin D deficiencies (levels<30 ng/ml) in pregnant women and their newborns was estimated to be 100% and 98.1%, respectively and mean concentration of 25 (OH) D for pregnant women and their newborns is very low. Therefore, vitamin D deficiency should be considered as a serious health priority.

 
Keyword(s): IRAN, PREGNANT WOMEN, NEWBORNS, VITAMIN D
 
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