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Paper Information

Journal:   MODARES MECHANICAL ENGINEERING   FEBRUARY 2017 , Volume 16 , Number 11 ; Page(s) 92 To 102.
 
Paper: 

IRON-CARBON MICRO PARTICLES DRUG TARGETING SIMULATION IN VERTEBROBASILAR SYSTEM: MAGNETIC FIELD EFFECTS

 
 
Author(s):  SALARI ALI, SHARIFI ALIREZA, NIAZMAND HAMID*
 
* DEPARTMENT OF MECHANICAL ENGINEERING, FERDOWSI UNIVERSITY OF MASHHAD, MASHHAD, IRAN
 
Abstract: 

Injection of drug micro particles into arteries is one of the stenosis treatments. Micro particles scattered in blood flow collide with plaques, the drug is absorbed to treat stenosis. Since the collision of drug particles with artery wall depends on blood flow pattern, the efficiency of this method relies on guiding drug particles to stenosed site, otherwise it would require much higher drug dose for the patient, which has various side effects. Applying magnetic field and guiding drug particles to the target area extensively increases efficiency of the treatment and lessens side effects. In the present study, efficiency of using drug particles in vertebrobasilar system to treat atherosclerosis with and without applying magnetic field has been investigated. Ansys-Fluent commercial software has been used for numerical simulation. Results indicate applying magnetic field plays an important role in drug particles circulation as drug captivation surges almost 16-fold. Injecting location and the particle diameters have also been examined and found to be important in the treatment effectiveness.

 
Keyword(s): VERTEBROBASILAR SYSTEM, VERTEBRAL ARTERY, ATHEROSCLEROSIS, MAGNETIC FIELD, MAGNETIC MICRO PARTICLES
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

SALARI, A., & SHARIFI, A., & NIAZMAND, H. (2017). IRON-CARBON MICRO PARTICLES DRUG TARGETING SIMULATION IN VERTEBROBASILAR SYSTEM: MAGNETIC FIELD EFFECTS. MODARES MECHANICAL ENGINEERING, 16(11 ), 92-102. https://www.sid.ir/en/journal/ViewPaper.aspx?id=571646



Vancouver: Copy

SALARI ALI, SHARIFI ALIREZA, NIAZMAND HAMID. IRON-CARBON MICRO PARTICLES DRUG TARGETING SIMULATION IN VERTEBROBASILAR SYSTEM: MAGNETIC FIELD EFFECTS. MODARES MECHANICAL ENGINEERING. 2017 [cited 2021July31];16(11 ):92-102. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=571646



IEEE: Copy

SALARI, A., SHARIFI, A., NIAZMAND, H., 2017. IRON-CARBON MICRO PARTICLES DRUG TARGETING SIMULATION IN VERTEBROBASILAR SYSTEM: MAGNETIC FIELD EFFECTS. MODARES MECHANICAL ENGINEERING, [online] 16(11 ), pp.92-102. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=571646.



 
 
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