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Paper Information

Journal:   MODARES JOURNAL OF MEDICAL SCIENCES (PATHOBIOLOGY)   WINTER 2017 , Volume 19 , Number 4 ; Page(s) 13 To 25.
 
Paper: 

THE EFFECT OF EIGHT WEEKS OF AEROBIC TRAINING ON LEPTIN, INTERLUKIN-6, AND TUMOR NECROSIS FACTOR-ALPHA LEVELS IN INACTIVE ELDERLY WOMEN

 
 
Author(s):  DOOSTDAR MEHDI, FATHEI MEHRDAD, HEJAZI KEYVAN*, KIANI GOL MOJTABA
 
* DEPARTMENT OF EXERCISE PHYSIOLOGY, FERDOWSI UNIVERSITY OF MASHHAD, MASHHAD, IRAN, POSTAL CODE: 48979-91779
 
Abstract: 

Objective: Atherosclerosis is the most common cause of coronary heart disease and a major cause of ischemic heart diseases. We have investigated the effect of eight weeks of aerobic training on the serum levels of leptin, IL-6, and TNF-? in inactive elderly women.
Methods: In this semi-experimental study, participants were selected by convenience sampling. We divided 21 subjects into two groups - active (n=10) and non-active (n=11). The program training included 60 min per session, 3 times per week for 8 weeks of aerobic exercise with 50-70 HRR%. Blood samples were taken before and after 8 weeks of aerobic training. We used the t-test for dependent and independent samples for intra- and intergroup comparisons. For all statistical comparisons, the level of significance was set at P<0.05.
Results: The aerobic training groups had a significant reduction in leptin (P=0.001), IL-6 (P=0.01), and TNF-? (P=0.001) after 8 weeks of aerobic training compared with the control group. The intergroup variations in weight, BMI, leptin, and TNF-
a had a significant change (P<0.05).
Conclusion: The results of the present study suggested that endurance training decreased leptin, IL-6, and TNF-
a levels, effectively improved cardiovascular health, and reduced the risk of atherosclerosis.

 
Keyword(s): LEPTIN, INTERLUKIN-6, AEROBIC EXERCISES, ELDERLY WOMEN
 
References: 
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