Paper Information

Journal:   IRANIAN JOURNAL OF RADIOLOGY   OCTOBER 2016 , Volume 13 , Number 4; Page(s) 0 To 0.
 
Paper: 

ASSESSING ABSORPTION COEFFICIENT OF HEMOGLOBIN IN THE BREAST PHANTOM USING NEAR-INFRARED SPECTROSCOPY

 
Author(s):  MEHNATI PARINAZ, JAFARI TIRTASH MAEDE*, ZAKERHAMIDI MOHAMMAD SADEGH, MEHNATI PARISA
 
* DEPARTMENT OF MEDICAL PHYSICS, SCHOOL OF MEDICINE, TABRIZ UNIVERSITY OF MEDICAL SCIENCES, TABRIZ, IRAN
 
Abstract: 

Background: Blood concentrations and oxygen saturation levels are important biomarkers for breast cancer diagnosis.
Objectives: In this study, the absorption coefficient of hemoglobin (Hb) was used to distinguish between normal and abnormal breast tissue.
Materials and Methods: A near-infrared source (637 nm) was transmitted from major and minor vessels of a breast phantom containing 2×, 4×concentrations of oxy- and deoxy-Hb. The absorption coefficients were determined from spectrometer (SM) and powermeter (PM) data.
Results: The absorption coefficients were 0.075
±0.026 cm-1 for oxygenated Hb (normal) in major vessels and 0.141±0.023 cm-1 at 4×concentration (abnormal) with SM, whereas the breast absorption coefficients were 0.099±0.017 cm-1 for oxygenated Hb (normal) in minor vessels and 0.171±0.005 cm-1 at 4×concentrations with SM. A comparison of the data obtained using a SM and a PM was not significant statistically.
Conclusion: The study of the absorption coefficient data of different concentrations of Hb in normal and abnormal breasts via the diffusion of near-infrared light is a valuable method and has the potential to aid in early detection of breast abnormalities with SM and PM in major and minor vessels.

 
Keyword(s): HEMOGLOBIN, OPTICAL PROPERTIES, NEAR INFRARED SPECTROSCOPY, ABSORPTION COEFFICIENT
 
References: 
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