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Paper Information

Journal:   JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)   2ND WEEK DECEMBER 2017 , Volume 35 , Number 450 ; Page(s) 1364 To 1369.
 
Paper: 

THE FREQUENCY OF CANDIDURIA IN HOSPITALIZED PATIENTS AT NEPHROLOGY DEPARTMENT, LABBAFINEJAD HOSPITAL, TEHRAN, IRAN

 
 
Author(s):  AZAD MOHSEN, CHABAVIZADEH JAVAHER*, DEHGHAN PARVIN, MOHAMMADI RASOUL
 
* DEPARTMENT OF MYCOLOGY AND PARASITOLOGY, SCHOOL OF MEDICINE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 

Background: Candiduria is one of the most common infections in hospitalized patients, which is created by the administration of long-term antibiotic, disseminated candidiasis, urinary tract problems, and having long-term urine catheter. Prevalence of the candiduria in women is more than men. The aim of present study was to determine the frequency of the Candida species of candiduria in hospitalized patients in nephrology department, Labbafinejad hospital, Tehran, Iran.
Methods: This study was carried out on 53 patients. The early identification of species was done using CHROMagar Candida medium. The genomic DNA was extracted using boiling method. Polymerase chain reaction (PCR) was used to amplify ITS1-5.8s-ITS2 region. The polymerase chain reaction products were then digested with MspI restriction enzyme. Polymerase chain reaction and restriction fragment length polymorphism (RFLP) products were revealed on 1.5% and 2% agarose gel electrophoresis, respectively, to identify the yeast.
Findings: Among 53 patients, 14 were diagnosed with candiduria. In our study, the frequency of candiduria was 26.4%. Separately, 5 patients (35.7%) were men and 9 (64.3%) were women. Candida glabrata (C. glabrata) had the highest frequency (42.8%). Other identified Candida species were C. albicans (21.4%), C. krusei (21.4%), C. tropicalis (7.2%), and C. parapsilosis (7.2%).
Conclusion: Increase in non-albicans species, due to resistance to antifungal drugs and increased use of immunosuppressive drugs, have resulted in many problems for candiduria treatment. Therefore, identification and appropriate treatment of these elements, especially in nephrology ward of hospitals, seems to be necessary.

 
Keyword(s): CANDIDIASIS, NEPHROLOGY, HOSPITAL
 
 
References: 
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Click to Cite.
APA: Copy

AZAD, M., & CHABAVIZADEH, J., & DEHGHAN, P., & MOHAMMADI, R. (2017). THE FREQUENCY OF CANDIDURIA IN HOSPITALIZED PATIENTS AT NEPHROLOGY DEPARTMENT, LABBAFINEJAD HOSPITAL, TEHRAN, IRAN. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 35(450 ), 1364-1369. https://www.sid.ir/en/journal/ViewPaper.aspx?id=569982



Vancouver: Copy

AZAD MOHSEN, CHABAVIZADEH JAVAHER, DEHGHAN PARVIN, MOHAMMADI RASOUL. THE FREQUENCY OF CANDIDURIA IN HOSPITALIZED PATIENTS AT NEPHROLOGY DEPARTMENT, LABBAFINEJAD HOSPITAL, TEHRAN, IRAN. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S). 2017 [cited 2021May12];35(450 ):1364-1369. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=569982



IEEE: Copy

AZAD, M., CHABAVIZADEH, J., DEHGHAN, P., MOHAMMADI, R., 2017. THE FREQUENCY OF CANDIDURIA IN HOSPITALIZED PATIENTS AT NEPHROLOGY DEPARTMENT, LABBAFINEJAD HOSPITAL, TEHRAN, IRAN. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), [online] 35(450 ), pp.1364-1369. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=569982.



 
 
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