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Paper Information

Journal:   IRANIAN JOURNAL OF MEDICAL PHYSICS   MARCH 2016 , Volume 13 , Number 1; Page(s) 1 To 7.
 
Paper: 

MONTE CARLO EVALUATION OF GAMMA KNIFE DOSE PROFILE IN REAL BRAIN PHANTOM

 
 
Author(s):  AGHAEBRAHIMIAN ALI*, ALAMATSAZ MOHAMMAD HASSAN
 
* DEPARTMENT OF PHYSICS, ISFAHAN UNIVERSITY OF TECHNOLOGY, ISFAHAN, IRAN
 
Abstract: 

Introduction: The Gamma Knife system is designed solely for non-invasive treatment of brain disorders, and it benefits from stereotactic surgical techniques. Dose calculations required in the system are performed by GammaPlan code; in this code, brain tissue is considered uniform. In the present study, we evaluated the effect of Gamma Knife system on the obtained dose through simulating a real human brain phantom.
Materials and Methods: In this study, a Monte Carlo simulation code (MCNPX2.7) was employed to simulate Gamma Knife system. Brain tissue equivalent Snyder phantom and combinations were considered according to International Commission on Radiological Units (ICRU) -44 report.
Results: To ensure accuracy of the simulations, patient’s head was modeled by a spherical water phantom. At this point, the dosimetry parameters were compared with those obtained by the Monte Carlo code EGS4 and good consistency was observed (less than 7% difference). At the next stage, the above dosimetry parameters were compared with those obtained experimentally by polystyrene phantom and EDR2 dosimetry film and improved consistency was detected (less than 0.5% difference). Finally, the Snyder phantom, as the human brain, was simulated. The Full Width at Half Maximum (FWHM) and penumbra decreased by 4.7% and 18%, respectively. Moreover, an isocenter dose reduction of 30-40%, compared to the water phantom, was noted.
Conclusion: The calculation of the real phantom showed that water and polystyrene could function similarly, while evaluating dosimetry parameters in the Gamma Knife system; thus, water and polystyrene are not appropriate phantom matters for this purpose.

 
Keyword(s): FILM DOSIMETRY, GAMMA KNIFE RADIOSURGERY, MONTE CARLO METHOD, SNYDER PHANTOM
 
 
References: 
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Click to Cite.
APA: Copy

AGHAEBRAHIMIAN, A., & ALAMATSAZ, M. (2016). MONTE CARLO EVALUATION OF GAMMA KNIFE DOSE PROFILE IN REAL BRAIN PHANTOM. IRANIAN JOURNAL OF MEDICAL PHYSICS, 13(1), 1-7. https://www.sid.ir/en/journal/ViewPaper.aspx?id=568958



Vancouver: Copy

AGHAEBRAHIMIAN ALI, ALAMATSAZ MOHAMMAD HASSAN. MONTE CARLO EVALUATION OF GAMMA KNIFE DOSE PROFILE IN REAL BRAIN PHANTOM. IRANIAN JOURNAL OF MEDICAL PHYSICS. 2016 [cited 2021May08];13(1):1-7. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=568958



IEEE: Copy

AGHAEBRAHIMIAN, A., ALAMATSAZ, M., 2016. MONTE CARLO EVALUATION OF GAMMA KNIFE DOSE PROFILE IN REAL BRAIN PHANTOM. IRANIAN JOURNAL OF MEDICAL PHYSICS, [online] 13(1), pp.1-7. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=568958.



 
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