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Paper Information

Journal:   JOURNAL OF REPRODUCTION AND INFERTILITY   2017 , Volume 18 , Number 3; Page(s) 267 To 279.
 
Paper: 

THE CHALLENGE OF HUMAN SPERMATOZOA PROTEOME: A SYSTEMATIC REVIEW

 
 
Author(s):  GILANY KAMBIZ*, MINAI TEHRANI ARASH, AMINI MEHDI, AGHAREZAEE NILOOFAR, ARJMAND BABAK
 
* REPRODUCTIVE BIOTECHNOLOGY RESEARCH CENTER, AVICENNA RESEARCH INSTITUTE, ACECR, TEHRAN, IRAN
 
Abstract: 

Currently, there are 20, 197 human protein-coding genes in the most expertly curated database (UniProtKB/Swiss-Pro). Big efforts have been made by the international consortium, the Chromosome-Centric Human Proteome Project (C-HPP) and independent researchers, to map human proteome. In brief, anno 2017 the human proteome was outlined. The male factor contributes to 50% of infertility in couples. However, there are limited human spermatozoa proteomic studies. Firstly, the development of the mapping of the human spermatozoa was analyzed. The human spermatozoa have been used as a model for missing proteins. It has been shown that human spermatozoa are excellent sources for finding missing proteins. Y chromosome proteome mapping is led by Iran. However, it seems that it is extremely challenging to map the human spermatozoa Y chromosome proteins based on current mass spectrometry-based proteomics technology. Post-translation modifications (PTMs) of human spermatozoa proteome are the most unexplored area and currently the exact role of PTMs in male infertility is unknown. Additionally, the clinical human spermatozoa proteomic analysis, anno 2017 was done in this study.

 
Keyword(s): HUMAN, PROTEOME, PROTEOMICS, SPERMATOZOA, Y CHROMOSOME
 
 
References: 
 
+ Click to Cite.
APA: Copy

GILANY, K., & MINAI TEHRANI, A., & AMINI, M., & Agharezaee, N., & ARJMAND, B. (2017). THE CHALLENGE OF HUMAN SPERMATOZOA PROTEOME: A SYSTEMATIC REVIEW. JOURNAL OF REPRODUCTION AND INFERTILITY, 18(3), 267-279. https://www.sid.ir/en/journal/ViewPaper.aspx?id=568541



Vancouver: Copy

GILANY KAMBIZ, MINAI TEHRANI ARASH, AMINI MEHDI, Agharezaee Niloofar, ARJMAND BABAK. THE CHALLENGE OF HUMAN SPERMATOZOA PROTEOME: A SYSTEMATIC REVIEW. JOURNAL OF REPRODUCTION AND INFERTILITY. 2017 [cited 2021May18];18(3):267-279. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=568541



IEEE: Copy

GILANY, K., MINAI TEHRANI, A., AMINI, M., Agharezaee, N., ARJMAND, B., 2017. THE CHALLENGE OF HUMAN SPERMATOZOA PROTEOME: A SYSTEMATIC REVIEW. JOURNAL OF REPRODUCTION AND INFERTILITY, [online] 18(3), pp.267-279. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=568541.



 
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