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Paper Information

Journal:   RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)   2003-2004 , Volume 8 , Number 5 (35); Page(s) 315 To 320.
 
Paper: 

PREVALENCE AND RISK FACTORS OF HEPATITIS C IN HEMODIALYSED PATIENTS

 
 
Author(s):  ALAVIAN M.*, EYN ELAHI BEHZAD, HAJARIZADEH B., BAKHTIARI S., NAFAR MOHSEN, AHRABI S.
 
* Dept. of Gastroenterology, Baghiatollah Medical Science University
 
Abstract: 

Backgrounds: Hepatitis C virus (HCV) infection is common among patients undergoing hemodialysis. Controlling HCV-related liver diseases is an important matter of health concern among such patients. Nowadays, liver diseases are a major cause of death in patients with end stage renal disease (ESRD). Materials and methods: To investigate the prevalence of HCV infection in patients on hemodialysis and its associated risk factors, we conducted a retrospective case series of 838 patients on hemodialysis in Tehran. Patients were selected randomly (cluster sampling) and all were checked for anti-HCV antibodies, using ELISA technique and then to confirm the positive samples with RlBA.
Results: Totally, 111 patients (13.2%) were infected. Considering univariate analysis, longer duration on hemodialysis (p=0.000), more weekly dialysis sessions (p=0.03), history of blood transfusion (p=0.03) and history of previous renal transplantation (p=0.01) were associated with higher rate of HCV infection. However, on multivariate analysis, hemodialysis duration (p=0.000) and blood transfusion (p=0.02) remain significant as risk factors for HCV acquisition. The more units transfused, the more the rate of HCV infection.
Conclusion: It seems that early transplantation and avoidance of blood transfusion as much as possible - for example by using erithropoietin- are the two most important practical interventions to reduce HCV exposure rate in patients on hemodialysis.

 
Keyword(s): BLOOD TRANSJUSION, HEPATITIS C, HEMODIALYSIS, KIDNEY FAILURE, RISKFACTORS
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

ALAVIAN, M., & EYN ELAHI, B., & HAJARIZADEH, B., & BAKHTIARI, S., & NAFAR, M., & AHRABI, S. (2004). PREVALENCE AND RISK FACTORS OF HEPATITIS C IN HEMODIALYSED PATIENTS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 8(5 (35)), 315-320. https://www.sid.ir/en/journal/ViewPaper.aspx?id=5443



Vancouver: Copy

ALAVIAN M., EYN ELAHI BEHZAD, HAJARIZADEH B., BAKHTIARI S., NAFAR MOHSEN, AHRABI S.. PREVALENCE AND RISK FACTORS OF HEPATITIS C IN HEMODIALYSED PATIENTS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH). 2004 [cited 2021June16];8(5 (35)):315-320. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=5443



IEEE: Copy

ALAVIAN, M., EYN ELAHI, B., HAJARIZADEH, B., BAKHTIARI, S., NAFAR, M., AHRABI, S., 2004. PREVALENCE AND RISK FACTORS OF HEPATITIS C IN HEMODIALYSED PATIENTS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), [online] 8(5 (35)), pp.315-320. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=5443.



 
 
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