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Paper Information

Journal:   MODERN GENETICS JOURNAL (MGJ)   FALL 2016 , Volume 11 , Number 3; Page(s) 459 To 467.
 
Paper: 

A GENOMIC SCAN FOR DETECTION OF SELECTION SIGNATURES USING SNP DATA IN AUSTRALIAN MERINO SHEEP

 
 
Author(s):  MONTAZERI M., ASADI FOZI M.*, ESMAEILIZADEH KOSHKOIEH A., FERDOSI M.H., VAN DER WERF J.
 
* DEPARTMENT OF ANIMAL SCIENCE, FACULTY OF AGRICULTURE, SHAHDI BAHONAR UNIVERSITY OF KERMAN, KERMAN, IRAN
 
Abstract: 

deciphering the genetic basis of phenotypic diversity is one of the main aims of biological research.
Domestic animals are useful tool for making substantial progress towards this goal. Selection signatures are the regions of the genome that are functionally important and therefore have been under either natural or artificial selection. In this paper, a whole genome scan was performed using 3000 individuals,
~50000 SNP markers from nine populations of Australian Merino sheep, with the aim of identifying divergently selected regions of the genome. Five genomic regions on 4 chromosomes were identified as putatively harboring selective sweeps. These regions were located on chromosomes 6, 7, 11 (two areas) and 26. These selected genomic regions were surveyed to find encoding putative candidate genes and 9 genes were extracted from areas Ovine Genome v3.1 Assembly.Study of the reported QTL in these regions of the sheep genome showed that they overlapped with QTL of economically important traits such as carcass yield, growth and wool traits. Further investigation of these regions in validation studies will help to identify the candidate genes for economically important traits in sheep breeds.

 
Keyword(s): GENOME SCAN, POPULATION DIFFERENTIATION, SIGNATURES OF SELECTION, SINGLE NUCLEOTIDE POLYMORPHISM
 
 
References: 
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Citations: 
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APA: Copy

MONTAZERI, M., & ASADI FOZI, M., & ESMAEILIZADEH KOSHKOIEH, A., & FERDOSI, M., & VAN DER WERF, J. (2016). A GENOMIC SCAN FOR DETECTION OF SELECTION SIGNATURES USING SNP DATA IN AUSTRALIAN MERINO SHEEP. MODERN GENETICS JOURNAL (MGJ), 11(3), 459-467. https://www.sid.ir/en/journal/ViewPaper.aspx?id=527240



Vancouver: Copy

MONTAZERI M., ASADI FOZI M., ESMAEILIZADEH KOSHKOIEH A., FERDOSI M.H., VAN DER WERF J.. A GENOMIC SCAN FOR DETECTION OF SELECTION SIGNATURES USING SNP DATA IN AUSTRALIAN MERINO SHEEP. MODERN GENETICS JOURNAL (MGJ). 2016 [cited 2021October20];11(3):459-467. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=527240



IEEE: Copy

MONTAZERI, M., ASADI FOZI, M., ESMAEILIZADEH KOSHKOIEH, A., FERDOSI, M., VAN DER WERF, J., 2016. A GENOMIC SCAN FOR DETECTION OF SELECTION SIGNATURES USING SNP DATA IN AUSTRALIAN MERINO SHEEP. MODERN GENETICS JOURNAL (MGJ), [online] 11(3), pp.459-467. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=527240.



 
 
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