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Paper Information

Journal:   JOURNAL OF KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES (BEHBOOD)   Fall 2003 , Volume 7 , Number 3; Page(s) 27 To 41.
 
Paper: 

SURVIVAL ANALYSIS OF RENAL TRANSPLANT RECIPIENTS IN KERMANSHAH PROVINCE (1989 - 2001 )

 
 
Author(s):  REZAEI MOHSEN, KAZEMNEJAD ANOUSHIRAVAN, RAEISI D., BABAEI G.H.
 
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Abstract: 

Background& Objective: The prevalence and annual incidence of end stage renal disease among 60 million Iranians is about 15000 and 3175 (53 patients per million), respectively. The first renal transplantation was performed in Shiraz, Iran in 1967. Iran has the most successful renal transplant program in the Middle East region. The renal transplant activity of the country has reached 24 renal transplants per million per year. The number of transplantation centers and transplantations has increased from 2 and 95 in 1986 to 21 and 951 in 1997, respectively. The kidney transplantation (KT) was started in Kermanshah, in 1989. Conflicting Survival rates of KT in Iran and world has been reported and there is no report from Kermanshah. In the present study, patient and graft survival rates of KT are reported.
Materials and methods: This study was done on 712 kidney transplant recipients in Kermanshah province and includes all KT recipients from 1989 to 2001. The variables that were analyzed include age, sex, dialysis time, and primary disease. Patient and graft survivals were calculated using Kaplan Meier method. Survival curves were compared with Log rank test. Comparison of data was done with Student's t test, chi square, and Fisher's exact test.
Results: Patient survival for recipients with a living unrelated donor (LURD) at 1, 3, and 10 years was 89.4, 82.4, and 61.4 months, respectively, and for recipients with a living related donor (LRD) 100, 97.3, and 72.6 percent. Graft survival for recipients with a living unrelated donor at 1, 3, and 10 years were 85.6, 77.2, and 33.3 respectively, and for recipients with a living related donor 97.4, 92.3 , and 60.6 percent Ranks were higher in recipients with a related donor.(Log rank, P=0.0056).
Discussion and Conclusions: Graft and patient survival rates obtained from our study are comparable to the reported results from other units in Iran and some Eastern European countries, higher than most countries of the former Soviet bloc, and less than USA, Japan and Western countries.

 
Keyword(s): KIDNEY TRANSPLANTATION, SURVIVAL ANALYSIS, LOG RANK TEST, KAPLAN MEIER METHOD, KERMANSHAH, FAMILY RELATIONSHIP
 
References: 
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