Paper Information

Journal:   JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES   Winter 2004 , Volume 11 , Number 1; Page(s) 28 To 35.
 
Paper: 

THE SITUATION OF NEW RISK FACTORS OF CARDIOVASCULAR DISEASE IN URBAN POPULATION OF ISFAHAN

 
 
Author(s):  NADERI GH., SARAFZADEGAN NAZILA, BOSHTAM M., AFYOONI A., ASGHARI S., JALALI A., NAJAFIYAN J., AMIRI M., SAMARIAN H., ZOU ALFAGHARI ANARAKI S., HAJARZADEH M.B., GHARIPOUR M.
 
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Abstract: 

During recent years, many epidemiological studies on risk factors of cardiovascular disease (CVD) have been preformed among which are fibrinogen, activity of factor VII, lipoprotein (a) , and hemocystein as new CVD risk factors. Through completed studies , it is found that in urban population of Isfahan more than one risk factor (hypertension , smoking , hypercholesterolemia , diabetes and obesity) are seen in 32% of men and a descriptive cross-sectional study was performed in 1998-99 and 409 subjects (175 men , 234 women) were randomly sample . Then each subject underwent a blood test, electrocardiography, medical examination and as 2-day recall. Personal information and anthropometric measurements were also recorded. Fast blood sugar & serum lipids were measured by auto analyzer Elan 2000, lipoprotein (a) by ELISA, hemocystein by HPLC, fibrinogen by turbidimetry and factor VII by calculating coagulation time compared to standard time. Statistical analyses were done by t-tests . The results showed that mean fibrinogen. Factor VII lipoprotein (a) , and hemocystein were 244.9±67 mg/dl, 118.3±58 per cent. 13.3±13 mg/dl and 11.5±3 mol /lit respectively in studied population. By comparing these new CVD risk factors over the world, it was determined that their levels were in the normal rage in urban population of Isfahan. The level of fibrinogen and hemocystein are higher and lower in women than those in men respectively that is compatible with many other studies.

 
Keyword(s): FIBRINOGEN, ACTIVITY OF FACTOR VII, LIPOPROTEIN (A), HEMOCYSTEIN, THROMBIN
 
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