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Paper Information

Journal:   AUDITORY AND VESTIBULAR RESEARCH   2016 , Volume 25 , Number 2; Page(s) 119 To 126.
 
Paper: 

THE PREVALENCE OF SENSORINEURAL HEARING LOSS IN PATIENTS WITH KAWASAKI DISEASE AFTER TREATMENT

 
 
Author(s):  TOOMAJ KHADIJE, AKBARIASBAGH PARVIN, KARIMI YAZDI ALIREZA*, AGHIGHI YAHYA, RAEESKARAMI SEYYED REZA, ESLAMBOL NASSAJ FARIBA, ALAMDARI SHAHNAZ
 
* OTORHINOLARYNGOLOGY RESEARCH CENTER, TEHRAN UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, 1145765111, IRAN
 
Abstract: 

Background and Aim: Kawasaki disease (KD) is an acute childhood febrile illness with worldwide incidence and the highest incidence occurs in Asian children, with coronary arteritis being the main complication. Sensorineural hearing loss (SNHL) has also been described as a complication of KD in several articles. The aim of this study was to evaluate the prevalence of SNHL in patients with KD treated with intra vein immunoglobellin (IVIG).
Methods: In this cross sectional study, we evaluated 56 patients who received KD treatment between 2011 and 2015 by auditory brainstem evoked response (ABR), pure tone audiometry (PTA), and tympanometry. Also, we evaluated the prevalence of coronary arteritis, the time of beginning IVIG treatment from the onset of fever, the prevalence of thrombocytosis, and erythrocyte sedimentation rate (ESR) in acute or subacute phases of their disease.
Results: During audiological evaluation, we found SNHL in one (2.6%) of the 36 patients. Other findings in the acute and subacute phases of KD included: 8 patients (22%) had coronary aneurysm, 17 (47%) thrombocytosis, 25 (69%) had elevated ESR, and the treatment with IVIG within 10 days of fever was done in 19 patients (53%).
Conclusion: SNHL is a complication of KD which could extend beyond the treatment time. In this study, the patient with SNHL was treated with KD two years before the study and in the acute phase of KD, he had thrombocytosis>500, 0000, ccoronary artery aneurysm, ESR> 40. The treatment with IVIG was done within the first 10 days of fever onset.

 
Keyword(s): KAWASAKI DISEASE, SENSORINEURAL HEARING LOSS, AUDITORY BRAINSTEM EVOKED RESPONSE, INTRA VEIN IMMUNOGLOBELLIN
 
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