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Paper Information

Journal:   JOURNAL OF ANIMAL BIOLOGY   SUMMER 2015 , Volume 7 , Number 4; Page(s) 45 To 51.
 
Paper: 

THE COMPARISON OF SERUMAL LEVEL OF PROLACTIN BETWEEN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME AND CONTROL GROUP

 
 
Author(s):  MOGHADDASI S.P., VAEZI GH.*, KALANTAR S.M.
 
* DEPARTMENT OF BIOLOGY, DAMGHAN BRANCH, ISLAMIC AZAD UNIVERSITY, DAMGHAN, IRAN
 
Abstract: 

Polycystic ovarian syndrome (PCOs) with prevalence between 5% to 10% is one of the most common endocrinologic disorders in women during reproductive age. Although, the cause of disease is not completely known, the serum level of some hormones is abnormal. The present study aimed to compare the serumal level of prolactin between women with polycystic ovarian syndrome and control group. This study was conducted during 2012 to 2013 in capital of eight provinces. In total 400 PCOs women and 500 control group were considered. The level of prolactin of serum was measured and the obtained data were analyzed by Mann-Witney test and Spearman correlation coefficient using SPSS software ver. 16.0 and the ROC curves were plotted. The mean serum prolactin level in patients group was 20.08±7.08 ng/ml (10.1- 50.26); while it was 17.08±2.77 ng/ml (12-23) in control group. Significantly higher in patients group (p<0.001). The results revealed the difference of prolactin level in the two groups. According to the present study, the relationship between high level of Prolactin and PCO could not be considered as a decisive symptom in the recognition of this disease. However, it is necessary to perform more studies in larger population samples.

 
Keyword(s): PCOS, SERUMAL LEVEL OF PROLACTIN, HYPERANDROGENISM, HYPERPROLACTINEMIA
 
References: 
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